SNP Detail For rs17819328
1.Mapping Information
Human SNP ID rs17819328
Human chromosome chr3
Human SNP position 12447843
Pig chromosome chr13
Pig SNP position 75662224
2.Annotation Information
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region3p25.2
Chromosome idchr3
Chromosome position12447843
Reported genePPARG
Mapped genePPARG
Upstream gene id
Downstream gene id
SNP gene ids5468
Upstream gene distance
Downstream gene distance
SNP risk allelers17819328-G
SNPsrs17819328
Merged0
SNP id current17819328
Contextintergenic_variant
Intergenic0
Allele frequency0.4318
P value0.00000000000005
Pvalue mlog13.3010299956639
P value text(EA, women)
Or beta0.0352
%95 Ci[0.026-0.044] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region3p25.2
Chromosome idchr3
Chromosome position12447843
Reported genePPARG
Mapped genePPARG
Upstream gene id
Downstream gene id
SNP gene ids5468
Upstream gene distance
Downstream gene distance
SNP risk allelers17819328-G
SNPsrs17819328
Merged0
SNP id current17819328
Contextintergenic_variant
Intergenic0
Allele frequency0.4317
P value0.000000002
Pvalue mlog8.69897000433601
P value text(EA)
Or beta0.0208
%95 Ci[0.014-0.028] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region3p25.2
Chromosome idchr3
Chromosome position12447843
Reported genePPARG
Mapped genePPARG
Upstream gene id
Downstream gene id
SNP gene ids5468
Upstream gene distance
Downstream gene distance
SNP risk allelers17819328-G
SNPsrs17819328
Merged0
SNP id current17819328
Contextintergenic_variant
Intergenic0
Allele frequency0.4277
P value0.00000000000004
Pvalue mlog13.397940008672
P value text(women)
Or beta0.0348
%95 Ci[0.026-0.044] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region3p25.2
Chromosome idchr3
Chromosome position12447843
Reported genePPARG
Mapped genePPARG
Upstream gene id
Downstream gene id
SNP gene ids5468
Upstream gene distance
Downstream gene distance
SNP risk allelers17819328-G
SNPsrs17819328
Merged0
SNP id current17819328
Contextintergenic_variant
Intergenic0
Allele frequency0.4302
P value0.0000000006
Pvalue mlog9.22184874961635
P value text
Or beta0.0211
%95 Ci[0.014-0.028] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782