Human SNP ID | rs17783561 |
---|---|
Human chromosome | chr10 |
Human SNP position | 109211677 |
Pig chromosome | chr14 |
Pig SNP position | 130612188 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 10q25.1 |
Chromosome id | chr10 |
Chromosome position | 109211677 |
Reported gene | NR |
Mapped gene | LOC105378478 - PHB2P1 |
Upstream gene id | 105378478 |
Downstream gene id | 645318 |
SNP gene ids | |
Upstream gene distance | 450053 |
Downstream gene distance | 316317 |
SNP risk allele | rs17783561-T |
SNPs | rs17783561 |
Merged | 0 |
SNP id current | 17783561 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.135585937974119 |
P value | 0.000006 |
Pvalue mlog | 5.22184874961635 |
P value text | (IGP56) |
Or beta | 0.2748 |
%95 Ci | [0.16-0.39] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |