Human SNP ID | rs17728338 |
---|---|
Human chromosome | chr5 |
Human SNP position | 151098757 |
Pig chromosome | chr16 |
Pig SNP position | 78149479 |
PubMed ID | 19169254 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19169254 |
Study | Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. |
Disease/Trait | Psoriasis |
Initial sample | 1,359 European ancestry cases, 1,400 European ancestry controls |
Replication sample | 5,048 European ancestry cases, 5,041 European ancestry controls |
Region | 5q33.1 |
Chromosome id | chr5 |
Chromosome position | 151098757 |
Reported gene | TNIP1 |
Mapped gene | TNIP1 - ANXA6 |
Upstream gene id | 10318 |
Downstream gene id | 309 |
SNP gene ids | |
Upstream gene distance | 11097 |
Downstream gene distance | 1949 |
SNP risk allele | rs17728338-A |
SNPs | rs17728338 |
Merged | 0 |
SNP id current | 17728338 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.054 |
P value | 1E-20 |
Pvalue mlog | 20 |
P value text | |
Or beta | 1.59 |
%95 Ci | [NR] |
Platform | Perlegen [~ 2500000] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST000322 |
PubMed ID | 25574825 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25574825 |
Study | Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms. |
Disease/Trait | Inflammatory skin disease |
Initial sample | 2,079 European ancestry atopic dermatitis cases, 4,212 European ancestry psoriasis cases, 11,899 European ancestry controls |
Replication sample | NA |
Region | 5q33.1 |
Chromosome id | chr5 |
Chromosome position | 151098757 |
Reported gene | ANXA6, TNIP1 |
Mapped gene | TNIP1 - ANXA6 |
Upstream gene id | 10318 |
Downstream gene id | 309 |
SNP gene ids | |
Upstream gene distance | 11097 |
Downstream gene distance | 1949 |
SNP risk allele | rs17728338-? |
SNPs | rs17728338 |
Merged | 0 |
SNP id current | 17728338 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 4E-38 |
Pvalue mlog | 37.397940008672 |
P value text | (Opposed) |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [~ 5200000] |
CNV | N |
Mapped trait | atopic eczema, psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000274, http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002740 |
PubMed ID | 25903422 |
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25903422 |
Study | Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. |
Disease/Trait | Psoriasis |
Initial sample | 3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls |
Replication sample | 5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls |
Region | 5q33.1 |
Chromosome id | chr5 |
Chromosome position | 151098757 |
Reported gene | TNIP1, ANXA6 |
Mapped gene | TNIP1 - ANXA6 |
Upstream gene id | 10318 |
Downstream gene id | 309 |
SNP gene ids | |
Upstream gene distance | 11097 |
Downstream gene distance | 1949 |
SNP risk allele | rs17728338-A |
SNPs | rs17728338 |
Merged | 0 |
SNP id current | 17728338 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.054 |
P value | 0.00000000000004 |
Pvalue mlog | 13.397940008672 |
P value text | (EA) |
Or beta | 1.64 |
%95 Ci | [1.44-1.86] |
Platform | Illumina [up to 4778154] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002874 |
PubMed ID | 25903422 |
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25903422 |
Study | Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. |
Disease/Trait | Psoriasis |
Initial sample | 3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls |
Replication sample | 5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls |
Region | 5q33.1 |
Chromosome id | chr5 |
Chromosome position | 151098757 |
Reported gene | TNIP1, ANXA6 |
Mapped gene | TNIP1 - ANXA6 |
Upstream gene id | 10318 |
Downstream gene id | 309 |
SNP gene ids | |
Upstream gene distance | 11097 |
Downstream gene distance | 1949 |
SNP risk allele | rs17728338-A |
SNPs | rs17728338 |
Merged | 0 |
SNP id current | 17728338 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.10115 |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | (Chinese) |
Or beta | 1.54 |
%95 Ci | [1.31-1.82] |
Platform | Illumina [up to 4778154] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002874 |
PubMed ID | 25903422 |
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25903422 |
Study | Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. |
Disease/Trait | Psoriasis |
Initial sample | 3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls |
Replication sample | 5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls |
Region | 5q33.1 |
Chromosome id | chr5 |
Chromosome position | 151098757 |
Reported gene | TNIP, ANXA6 |
Mapped gene | TNIP1 - ANXA6 |
Upstream gene id | 10318 |
Downstream gene id | 309 |
SNP gene ids | |
Upstream gene distance | 11097 |
Downstream gene distance | 1949 |
SNP risk allele | rs17728338-A |
SNPs | rs17728338 |
Merged | 0 |
SNP id current | 17728338 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.054 |
P value | 6E-20 |
Pvalue mlog | 19.2218487496163 |
P value text | |
Or beta | 1.6 |
%95 Ci | [1.45-1.77] |
Platform | Illumina [up to 4778154] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002874 |
PubMed ID | 26626624 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26626624 |
Study | Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. |
Disease/Trait | Cutaneous psoriasis |
Initial sample | 1,363 European ancestry cases, 4,934 European ancestry controls |
Replication sample | up to 2,969 European ancestry cases, up to European ancestry 14,384 controls |
Region | 5q33.1 |
Chromosome id | chr5 |
Chromosome position | 151098757 |
Reported gene | TNIP1 |
Mapped gene | TNIP1 - ANXA6 |
Upstream gene id | 10318 |
Downstream gene id | 309 |
SNP gene ids | |
Upstream gene distance | 11097 |
Downstream gene distance | 1949 |
SNP risk allele | rs17728338-A |
SNPs | rs17728338 |
Merged | 0 |
SNP id current | 17728338 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.00000000000002 |
Pvalue mlog | 13.698970004336 |
P value text | |
Or beta | 1.557 |
%95 Ci | NR |
Platform | Illumina [11532644] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST003269 |