SNP Detail For rs17679567
1.Mapping Information
Human SNP ID rs17679567
Human chromosome chr16
Human SNP position 76856229
Pig chromosome chr3
Pig SNP position 2466822
2.Annotation Information
PubMed ID22569225
JournalPharmacogenet Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/22569225
StudyInvestigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis.
Disease/TraitResponse to TNF-alpha inhibitors in rheumatoid arthritis
Initial sample196 European ancestry cases
Replication sampleNA
Region16q23.1
Chromosome idchr16
Chromosome position76856229
Reported geneCNTNAP4
Mapped geneLOC105376774 - MIR4719
Upstream gene id105376774
Downstream gene id100616172
SNP gene ids
Upstream gene distance83298
Downstream gene distance12707
SNP risk allelers17679567-?
SNPsrs17679567
Merged0
SNP id current17679567
Contextintron_variant
Intergenic1
Allele frequencyNR
P value0.000009
Pvalue mlog5.04575749056067
P value text(Relative change in DAS28)
Or beta
%95 Ci
PlatformIllumina [486450]
CNVN
Mapped traitrheumatoid arthritis, response to TNF antagonist
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0004653
Study accessionGCST001510