Human SNP ID | rs17679567 |
---|---|
Human chromosome | chr16 |
Human SNP position | 76856229 |
Pig chromosome | chr3 |
Pig SNP position | 2466822 |
PubMed ID | 22569225 |
---|---|
Journal | Pharmacogenet Genomics |
Link | www.ncbi.nlm.nih.gov/pubmed/22569225 |
Study | Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis. |
Disease/Trait | Response to TNF-alpha inhibitors in rheumatoid arthritis |
Initial sample | 196 European ancestry cases |
Replication sample | NA |
Region | 16q23.1 |
Chromosome id | chr16 |
Chromosome position | 76856229 |
Reported gene | CNTNAP4 |
Mapped gene | LOC105376774 - MIR4719 |
Upstream gene id | 105376774 |
Downstream gene id | 100616172 |
SNP gene ids | |
Upstream gene distance | 83298 |
Downstream gene distance | 12707 |
SNP risk allele | rs17679567-? |
SNPs | rs17679567 |
Merged | 0 |
SNP id current | 17679567 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000009 |
Pvalue mlog | 5.04575749056067 |
P value text | (Relative change in DAS28) |
Or beta | |
%95 Ci | |
Platform | Illumina [486450] |
CNV | N |
Mapped trait | rheumatoid arthritis, response to TNF antagonist |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0004653 |
Study accession | GCST001510 |