Human SNP ID | rs17651189 |
---|---|
Human chromosome | chr22 |
Human SNP position | 24448915 |
Pig chromosome | chr14 |
Pig SNP position | 52936297 |
PubMed ID | 24927181 |
---|---|
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/24927181 |
Study | Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. |
Disease/Trait | Acne (severe) |
Initial sample | 1,893 European ancestry cases, 5,132 European ancestry controls |
Replication sample | 2,063 European ancestry cases, 1,970 European ancestry controls |
Region | 22q11.23 |
Chromosome id | chr22 |
Chromosome position | 24448915 |
Reported gene | SNRPD3, SPECC1L, TMEM211, TOP1P2, UNQ2565, UPB1, GSTT1, SUSD2, GGT5, ADORA2A, ADORA2A-AS1, BCRP3, CABIN1, DKFZp434K191, DQ570150, DQ571461, DQ576853, EU036692, FAM211B, GGT1, GSTTP2, GUCD1, LOC391322, PIWIL3, POM121L10P, POM121L9P, SGSM1 |
Mapped gene | ADORA2A-AS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 646023 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs17651189-C |
SNPs | rs17651189 |
Merged | 0 |
SNP id current | 17651189 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.0507 |
P value | 0.0000006 |
Pvalue mlog | 6.22184874961635 |
P value text | |
Or beta | 1.44 |
%95 Ci | [1.24-1.68] |
Platform | Illumina [7300000] (imputed) |
CNV | N |
Mapped trait | acne |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003894 |
Study accession | GCST002481 |