SNP Detail For rs176095
1.Mapping Information
Human SNP ID rs176095
Human chromosome chr6
Human SNP position 32190542
Pig chromosome chr7
Pig SNP position 28048241
2.Annotation Information
PubMed ID23042114
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23042114
StudyGenome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
Disease/TraitAtopic dermatitis
Initial sample1,472 Japanese ancestry cases, 7,971 Japanese ancestry controls
Replication sample1,856 Japanese ancestry cases, 7,021 Japanese ancestry controls
Region6p21.32
Chromosome idchr6
Chromosome position32190542
Reported geneGPSM3
Mapped genePBX2 - GPSM3
Upstream gene id5089
Downstream gene id63940
SNP gene ids
Upstream gene distance356
Downstream gene distance224
SNP risk allelers176095-T
SNPsrs176095
Merged0
SNP id current176095
Contextupstream_gene_variant
Intergenic1
Allele frequency0.81
P value8E-20
Pvalue mlog19.096910013008
P value text
Or beta1.4
%95 Ci[1.30-1.51]
PlatformIllumina [606164]
CNVN
Mapped traitatopic eczema
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000274
Study accessionGCST001709
PubMed ID25574825
JournalAm J Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25574825
StudyGenome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms.
Disease/TraitAtopic dermatitis
Initial sample2,079 European ancestry cases, 3,867 European ancestry controls
Replication sampleNA
Region6p21.32
Chromosome idchr6
Chromosome position32190542
Reported geneGPSM3
Mapped genePBX2 - GPSM3
Upstream gene id5089
Downstream gene id63940
SNP gene ids
Upstream gene distance356
Downstream gene distance224
SNP risk allelers176095-G
SNPsrs176095
Merged0
SNP id current176095
Contextupstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.0000003
Pvalue mlog6.52287874528033
P value text
Or beta1.3020833
%95 Ci[1.18-1.44]
PlatformAffymetrix, Illumina, Perlegen [up to 5493100] (imputed)
CNVN
Mapped traitatopic eczema
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000274
Study accessionGCST002737