SNP Detail For rs17560407
1.Mapping Information
Human SNP ID rs17560407
Human chromosome chr5
Human SNP position 88887834
Pig chromosome JH118518-1
Pig SNP position 164116
2.Annotation Information
PubMed ID23400010
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/23400010
StudyGenome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
Disease/TraitThiazide-induced adverse metabolic effects in hypertensive patients
Initial sample425 European ancestry cases, 342 African American cases
Replication sampleNA
Region5q14.3
Chromosome idchr5
Chromosome position88887834
Reported geneMEF2C
Mapped geneMEF2C, MEF2C-AS1
Upstream gene id
Downstream gene id
SNP gene ids4208, 101929423
Upstream gene distance
Downstream gene distance
SNP risk allelers17560407-G
SNPsrs17560407
Merged0
SNP id current17560407
Contextintron_variant
Intergenic0
Allele frequency0.27
P value0.0000005
Pvalue mlog6.30102999566398
P value text(EA-triglyceride response)
Or beta23.23
%95 Ci[14.14-32.32] mg/dL decrease
PlatformAffymetrix, Illumina [> 2000000] (imputed)
CNVN
Mapped traitresponse to hydrochlorothiazide, triglyceride measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005202, http://www.ebi.ac.uk/efo/EFO_0004530
Study accessionGCST001859