Human SNP ID | rs17530068 |
---|---|
Human chromosome | chr6 |
Human SNP position | 81483392 |
Pig chromosome | chr1 |
Pig SNP position | 95392512 |
PubMed ID | 22976474 |
---|---|
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22976474 |
Study | A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. |
Disease/Trait | Breast cancer |
Initial sample | 3,666 European ancestry cases, 28,864 European ancestry controls, 1,004 African American cases, 2,744 African American controls |
Replication sample | 562 European ancestry cases, 6,410 European ancestry controls, 84 Japanese ancestry cases, 830 Japanese ancestry controls, 300 Latino cases, 1,164 Latino controls |
Region | 6q14.1 |
Chromosome id | chr6 |
Chromosome position | 81483392 |
Reported gene | FAM46A, C6orf37 |
Mapped gene | LOC105377870 - LOC101928742 |
Upstream gene id | 105377870 |
Downstream gene id | 101928742 |
SNP gene ids | |
Upstream gene distance | 559354 |
Downstream gene distance | 8047 |
SNP risk allele | rs17530068-C |
SNPs | rs17530068 |
Merged | 0 |
SNP id current | 17530068 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.24 |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | |
Or beta | 1.16 |
%95 Ci | [1.10-1.23] |
Platform | Illumina [2608509] (imputed) |
CNV | N |
Mapped trait | breast carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000305 |
Study accession | GCST001683 |
PubMed ID | 23535729 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23535729 |
Study | Large-scale genotyping identifies 41 new loci associated with breast cancer risk. |
Disease/Trait | Breast cancer |
Initial sample | 10,052 European ancestry cases, 12,575 European ancestry controls |
Replication sample | 45,290 European ancestry cases, 41,880 European ancestry controls |
Region | 6q14.1 |
Chromosome id | chr6 |
Chromosome position | 81483392 |
Reported gene | intergenic |
Mapped gene | LOC105377870 - LOC101928742 |
Upstream gene id | 105377870 |
Downstream gene id | 101928742 |
SNP gene ids | |
Upstream gene distance | 559354 |
Downstream gene distance | 8047 |
SNP risk allele | rs17530068-G |
SNPs | rs17530068 |
Merged | 0 |
SNP id current | 17530068 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.22 |
P value | 0.000000008 |
Pvalue mlog | 8.09691001300805 |
P value text | |
Or beta | 1.05 |
%95 Ci | [1.03-1.08] |
Platform | Affymetrix, Illumina [~ 2600000] (imputed) |
CNV | N |
Mapped trait | breast carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000305 |
Study accession | GCST001937 |
PubMed ID | 23535733 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23535733 |
Study | Genome-wide association studies identify four ER negative-specific breast cancer risk loci. |
Disease/Trait | Breast cancer |
Initial sample | 4,193 European ancestry cases, 35,194 European ancestry controls |
Replication sample | 6,514 European ancestry cases, 41,455 European ancestry controls |
Region | 6q14.1 |
Chromosome id | chr6 |
Chromosome position | 81483392 |
Reported gene | intergenic |
Mapped gene | LOC105377870 - LOC101928742 |
Upstream gene id | 105377870 |
Downstream gene id | 101928742 |
SNP gene ids | |
Upstream gene distance | 559354 |
Downstream gene distance | 8047 |
SNP risk allele | rs17530068-C |
SNPs | rs17530068 |
Merged | 0 |
SNP id current | 17530068 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.237 |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | |
Or beta | 1.09 |
%95 Ci | [1.05-1.13] |
Platform | Illumina [NR] |
CNV | N |
Mapped trait | breast carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000305 |
Study accession | GCST001930 |