Human SNP ID | rs17518584 |
---|---|
Human chromosome | chr3 |
Human SNP position | 85555773 |
Pig chromosome | chr13 |
Pig SNP position | 181277774 |
PubMed ID | 25869804 |
---|---|
Journal | Mol Psychiatry |
Link | www.ncbi.nlm.nih.gov/pubmed/25869804 |
Study | GWAS for executive function and processing speed suggests involvement of the CADM2 gene. |
Disease/Trait | Information processing speed |
Initial sample | Up to 30,807 European ancestry individuals, up to 1,267 Erasmus Rucphen Family individuals, up to 535 Korkulan individuals, up to 417 Orcadian individuals, up to 311 Vis individuals |
Replication sample | Up to 8,436 European ancestry individuals, up to 1,444 African American individuals |
Region | 3p12.1 |
Chromosome id | chr3 |
Chromosome position | 85555773 |
Reported gene | CADM2 |
Mapped gene | CADM2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 253559 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs17518584-T |
SNPs | rs17518584 |
Merged | 0 |
SNP id current | 17518584 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.64 |
P value | 0.000000003 |
Pvalue mlog | 8.52287874528033 |
P value text | (LDST/DSST- age, sex, and education adjusted) |
Or beta | 5.92 |
%95 Ci | [NR] unit increase |
Platform | Affymetrix, Illumina [up to 2357391] (imputed) |
CNV | N |
Mapped trait | information processing speed |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004363 |
Study accession | GCST002850 |
PubMed ID | 25644384 |
Journal | Mol Psychiatry |
Link | www.ncbi.nlm.nih.gov/pubmed/25644384 |
Study | Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53鈥?49). |
Disease/Trait | Cognitive function |
Initial sample | 51,719 European ancestry individuals 1,473 Erasmus Rupchen Family individuals, 327 Korculan individuals, 430 Orcadian individuals |
Replication sample | NA |
Region | 3p12.1 |
Chromosome id | chr3 |
Chromosome position | 85555773 |
Reported gene | CADM2 |
Mapped gene | CADM2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 253559 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs17518584-? |
SNPs | rs17518584 |
Merged | 0 |
SNP id current | 17518584 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | |
Or beta | 0.0282 |
%95 Ci | [0.017-0.040] unit increase |
Platform | Affymetrix, Illumina [2478500] (imputed) |
CNV | N |
Mapped trait | cognition |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003925 |
Study accession | GCST002774 |