SNP Detail For rs17483548
1.Mapping Information
Human SNP ID rs17483548
Human chromosome chr15
Human SNP position 78437971
Pig chromosome chr7
Pig SNP position 53022221
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78437971
Reported geneIntergenic
Mapped geneLOC105370912 - IREB2
Upstream gene id105370912
Downstream gene id3658
SNP gene ids
Upstream gene distance28038
Downstream gene distance205
SNP risk allelers17483548-A
SNPsrs17483548
Merged0
SNP id current17483548
Contextintron_variant
Intergenic1
Allele frequency0.336
P value0.0000000000003
Pvalue mlog12.5228787452803
P value text
Or beta0.074
%95 CiNR unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio in COPD
Initial sample5,439 European ancestry current and former smoker cases, 821 African American current and former smoker cases
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78437971
Reported geneIntergenic
Mapped geneLOC105370912 - IREB2
Upstream gene id105370912
Downstream gene id3658
SNP gene ids
Upstream gene distance28038
Downstream gene distance205
SNP risk allelers17483548-A
SNPsrs17483548
Merged0
SNP id current17483548
Contextintron_variant
Intergenic1
Allele frequency0.386
P value0.000003
Pvalue mlog5.52287874528033
P value text
Or beta0.012
%95 CiNR unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, chronic obstructive pulmonary disease, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0000341, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003265
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78437971
Reported geneIntergenic
Mapped geneLOC105370912 - IREB2
Upstream gene id105370912
Downstream gene id3658
SNP gene ids
Upstream gene distance28038
Downstream gene distance205
SNP risk allelers17483548-A
SNPsrs17483548
Merged0
SNP id current17483548
Contextintron_variant
Intergenic1
Allele frequency0.332
P value0.000000000003
Pvalue mlog11.5228787452803
P value text
Or beta0.015
%95 Ciunit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264