SNP Detail For rs17465637
1.Mapping Information
Human SNP ID rs17465637
Human chromosome chr1
Human SNP position 222650187
Pig chromosome chr10
Pig SNP position 13553705
2.Annotation Information
PubMed ID17634449
JournalN Engl J Med
Linkwww.ncbi.nlm.nih.gov/pubmed/17634449
StudyGenomewide association analysis of coronary artery disease.
Disease/TraitCoronary heart disease
Initial sample1,926 European ancestry cases, 2,938 European ancestry controls
Replication sample875 European ancestry cases, 1,644 European ancestry controls
Region1q41
Chromosome idchr1
Chromosome position222650187
Reported geneMIA3
Mapped geneMIA3
Upstream gene id
Downstream gene id
SNP gene ids375056
Upstream gene distance
Downstream gene distance
SNP risk allelers17465637-C
SNPsrs17465637
Merged0
SNP id current17465637
Contextintron_variant
Intergenic0
Allele frequency0.71
P value0.000001
Pvalue mlog6
P value text
Or beta1.2
%95 Ci[1.12-1.30]
PlatformAffymetrix [377857]
CNVN
Mapped traitcoronary heart disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001645
Study accessionGCST000057
PubMed ID19198609
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19198609
StudyGenome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
Disease/TraitMyocardial infarction (early onset)
Initial sample2,967 European ancestry cases, 3,075 European ancestry controls
Replication sample9,746 European ancestry cases, 9,746 European ancestry controls
Region1q41
Chromosome idchr1
Chromosome position222650187
Reported geneMIA3
Mapped geneMIA3
Upstream gene id
Downstream gene id
SNP gene ids375056
Upstream gene distance
Downstream gene distance
SNP risk allelers17465637-C
SNPsrs17465637
Merged0
SNP id current17465637
Contextintron_variant
Intergenic0
Allele frequency0.72
P value0.000000001
Pvalue mlog9
P value text
Or beta1.14
%95 Ci[1.10-1.19]
PlatformAffymetrix [~ 2500000] (imputed)
CNVN
Mapped traitmyocardial infarction
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000612
Study accessionGCST000340
PubMed ID21378990
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21378990
StudyLarge-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
Disease/TraitCoronary heart disease
Initial sample22,233 European ancestry cases, 64,762 European ancestry controls
Replication sample56,682 European ancestry cases and controls
Region1q41
Chromosome idchr1
Chromosome position222650187
Reported geneMIA3
Mapped geneMIA3
Upstream gene id
Downstream gene id
SNP gene ids375056
Upstream gene distance
Downstream gene distance
SNP risk allelers17465637-C
SNPsrs17465637
Merged0
SNP id current17465637
Contextintron_variant
Intergenic0
Allele frequency0.74
P value0.00000001
Pvalue mlog8
P value text
Or beta1.14
%95 Ci[1.09-1.20]
PlatformAffymetrix, Illumina [~ 2300000] (imputed)
CNVN
Mapped traitcoronary heart disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001645
Study accessionGCST000998