SNP Detail For rs1746048
1.Mapping Information
Human SNP ID rs1746048
Human chromosome chr10
Human SNP position 44280376
Pig chromosome chr14
Pig SNP position 100073322
2.Annotation Information
PubMed ID19198609
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19198609
StudyGenome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
Disease/TraitMyocardial infarction (early onset)
Initial sample2,967 European ancestry cases, 3,075 European ancestry controls
Replication sample9,746 European ancestry cases, 9,746 European ancestry controls
Region10q11.21
Chromosome idchr10
Chromosome position44280376
Reported geneCXCL12
Mapped geneLINC00841 - LOC101929465
Upstream gene id283033
Downstream gene id101929465
SNP gene ids
Upstream gene distance310469
Downstream gene distance11712
SNP risk allelers1746048-C
SNPsrs1746048
Merged0
SNP id current1746048
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.84
P value0.000000007
Pvalue mlog8.15490195998574
P value text
Or beta1.17
%95 Ci[1.11-1.24]
PlatformAffymetrix [~ 2500000] (imputed)
CNVN
Mapped traitmyocardial infarction
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000612
Study accessionGCST000340
PubMed ID21378990
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21378990
StudyLarge-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
Disease/TraitCoronary heart disease
Initial sample22,233 European ancestry cases, 64,762 European ancestry controls
Replication sample56,682 European ancestry cases and controls
Region10q11.21
Chromosome idchr10
Chromosome position44280376
Reported geneCXCL12
Mapped geneLINC00841 - LOC101929465
Upstream gene id283033
Downstream gene id101929465
SNP gene ids
Upstream gene distance310469
Downstream gene distance11712
SNP risk allelers1746048-C
SNPsrs1746048
Merged0
SNP id current1746048
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.87
P value0.0000000003
Pvalue mlog9.52287874528033
P value text
Or beta1.09
%95 Ci[1.07-1.13]
PlatformAffymetrix, Illumina [~ 2300000] (imputed)
CNVN
Mapped traitcoronary heart disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001645
Study accessionGCST000998