Human SNP ID | rs174601 |
---|---|
Human chromosome | chr11 |
Human SNP position | 61855668 |
Pig chromosome | chr2 |
Pig SNP position | 9142390 |
PubMed ID | 22001757 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22001757 |
Study | Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. |
Disease/Trait | Liver enzyme levels (alkaline phosphatase) |
Initial sample | Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals |
Replication sample | NA |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61855668 |
Reported gene | FADS1, FADS2, C11orf10 |
Mapped gene | FADS2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 9415 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174601-T |
SNPs | rs174601 |
Merged | 0 |
SNP id current | 174601 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.35 |
P value | 0.000000003 |
Pvalue mlog | 8.52287874528033 |
P value text | |
Or beta | 1.7 |
%95 Ci | [0.80-2.60] % increase |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | alkaline phosphatase measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004533 |
Study accession | GCST001276 |
PubMed ID | 24816252 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24816252 |
Study | An atlas of genetic influences on human blood metabolites. |
Disease/Trait | Blood metabolite levels |
Initial sample | 7,824 European ancestry individuals |
Replication sample | NA |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61855668 |
Reported gene | FADS1 |
Mapped gene | FADS2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 9415 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174601-T |
SNPs | rs174601 |
Merged | 0 |
SNP id current | 174601 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.34 |
P value | 0.0000000000000008 |
Pvalue mlog | 15.096910013008 |
P value text | (stearidonate (18:4n3)) |
Or beta | 0.034 |
%95 Ci | [0.026-0.042] unit decrease |
Platform | Affymetrix, Illumina [2100000] (imputed) |
CNV | N |
Mapped trait | blood metabolite measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005664 |
Study accession | GCST002443 |
PubMed ID | 25646338 |
Journal | Am J Clin Nutr |
Link | www.ncbi.nlm.nih.gov/pubmed/25646338 |
Study | Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. |
Disease/Trait | Trans fatty acid levels |
Initial sample | 8,013 European ancestry individuals |
Replication sample | 1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61855668 |
Reported gene | NR |
Mapped gene | FADS2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 9415 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174601-T |
SNPs | rs174601 |
Merged | 0 |
SNP id current | 174601 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.3731 |
P value | 0.0000000000003 |
Pvalue mlog | 12.5228787452803 |
P value text | (Cis/trans-18:2, EA) |
Or beta | 0.0034 |
%95 Ci | [0.0024-0.0044] unit increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | cis/trans-18:2 fatty acid measurement, trans fatty acid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006824, http://www.ebi.ac.uk/efo/EFO_0006821 |
Study accession | GCST002721 |
PubMed ID | 25500335 |
Journal | Prostaglandins Leukot Essent Fatty Acids |
Link | www.ncbi.nlm.nih.gov/pubmed/25500335 |
Study | A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study. |
Disease/Trait | Red blood cell fatty acid levels |
Initial sample | 2,633 individuals |
Replication sample | NA |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61855668 |
Reported gene | C11orf9, C11orf10, FEN1, FADS1, FADS2, RAB3IL1, DAGLA, BEST1 |
Mapped gene | FADS2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 9415 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174601-? |
SNPs | rs174601 |
Merged | 0 |
SNP id current | 174601 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.35 |
P value | 3E-305 |
Pvalue mlog | 304.52287874528 |
P value text | (DGLA) |
Or beta | 0.591 |
%95 Ci | [NR] unit increase |
Platform | Affymetrix [~ 2500000] (imputed) |
CNV | N |
Mapped trait | fatty acid measurement, linolenic acid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0006811 |
Study accession | GCST002712 |