Human SNP ID | rs174555 |
---|---|
Human chromosome | chr11 |
Human SNP position | 61812288 |
Pig chromosome | chr2 |
Pig SNP position | 9259318 |
PubMed ID | 24823311 |
---|---|
Journal | Circ Cardiovasc Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24823311 |
Study | Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. |
Disease/Trait | Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) |
Initial sample | 8,631 European ancestry individuals |
Replication sample | NA |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61812288 |
Reported gene | FTH1, C11orf9, FADS1, DAGLA, FADS2, FEN1, C11orf10, FADS3, RAB3IL1, BEST1 |
Mapped gene | FADS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3992 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174555-T |
SNPs | rs174555 |
Merged | 0 |
SNP id current | 174555 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.71 |
P value | 5E-168 |
Pvalue mlog | 167.301029995663 |
P value text | |
Or beta | 0.39 |
%95 Ci | [NR] unit decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | omega-6 polyunsaturated fatty acid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005680 |
Study accession | GCST002444 |
PubMed ID | 26068415 |
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/26068415 |
Study | Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. |
Disease/Trait | Glycerophospholipid levels |
Initial sample | up to 7,478 European ancestry individuals |
Replication sample | 1,182 European ancestry individuals |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61812288 |
Reported gene | FADS1, FADS2, FADS3 |
Mapped gene | FADS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3992 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174555-T |
SNPs | rs174555 |
Merged | 0 |
SNP id current | 174555 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.713 |
P value | 1E-35 |
Pvalue mlog | 35 |
P value text | (Phosphatidylcholine diacyl C36:3) |
Or beta | 0.0553 |
%95 Ci | [0.047-0.064] unit decrease |
Platform | Affymetrix, Illumina [at least 296619] (imputed) |
CNV | N |
Mapped trait | glycerophospholipid measurement, blood metabolite measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0007630, http://www.ebi.ac.uk/efo/EFO_0005664 |
Study accession | GCST002965 |
PubMed ID | 25646338 |
Journal | Am J Clin Nutr |
Link | www.ncbi.nlm.nih.gov/pubmed/25646338 |
Study | Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. |
Disease/Trait | Trans fatty acid levels |
Initial sample | 8,013 European ancestry individuals |
Replication sample | 1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61812288 |
Reported gene | NR |
Mapped gene | FADS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3992 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174555-T |
SNPs | rs174555 |
Merged | 0 |
SNP id current | 174555 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.7057 |
P value | 0.000000000000006 |
Pvalue mlog | 14.2218487496163 |
P value text | (Cis/trans-18:2, EA) |
Or beta | 0.0034 |
%95 Ci | [0.0026-0.0042] unit decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | cis/trans-18:2 fatty acid measurement, trans fatty acid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006824, http://www.ebi.ac.uk/efo/EFO_0006821 |
Study accession | GCST002721 |