Human SNP ID | rs174545 |
---|---|
Human chromosome | chr11 |
Human SNP position | 61801834 |
Pig chromosome | chr2 |
Pig SNP position | 9250333 |
PubMed ID | 26584805 |
---|---|
Journal | Genes Nutr |
Link | www.ncbi.nlm.nih.gov/pubmed/26584805 |
Study | A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population. |
Disease/Trait | Delta-6 desaturase activity |
Initial sample | 717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls |
Replication sample | NA |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61801834 |
Reported gene | NR |
Mapped gene | FADS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3992 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174545-G |
SNPs | rs174545 |
Merged | 0 |
SNP id current | 174545 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.6561 |
P value | 5E-37 |
Pvalue mlog | 36.3010299956639 |
P value text | |
Or beta | 0.2367 |
%95 Ci | [0.20-0.27] unit decrease |
Platform | Illumina [up to 1980188] (imputed) |
CNV | N |
Mapped trait | |
Mapped trait URI | |
Study accession | GCST003244 |
PubMed ID | 25646338 |
Journal | Am J Clin Nutr |
Link | www.ncbi.nlm.nih.gov/pubmed/25646338 |
Study | Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. |
Disease/Trait | Trans fatty acid levels |
Initial sample | 8,013 European ancestry individuals |
Replication sample | 1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61801834 |
Reported gene | NR |
Mapped gene | FADS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3992 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174545-C |
SNPs | rs174545 |
Merged | 0 |
SNP id current | 174545 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.6702 |
P value | 0.00000000000007 |
Pvalue mlog | 13.1549019599857 |
P value text | (Cis/trans-18:2, EA) |
Or beta | 0.0031 |
%95 Ci | [0.0023-0.0039] unit decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | cis/trans-18:2 fatty acid measurement, trans fatty acid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006824, http://www.ebi.ac.uk/efo/EFO_0006821 |
Study accession | GCST002721 |
PubMed ID | 25500335 |
Journal | Prostaglandins Leukot Essent Fatty Acids |
Link | www.ncbi.nlm.nih.gov/pubmed/25500335 |
Study | A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study. |
Disease/Trait | Red blood cell fatty acid levels |
Initial sample | 2,633 individuals |
Replication sample | NA |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61801834 |
Reported gene | FADS1, C11orf10, C11orf9, FADS2, FEN1, FADS3, RAB3IL1 |
Mapped gene | FADS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3992 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174545-? |
SNPs | rs174545 |
Merged | 0 |
SNP id current | 174545 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.33 |
P value | 8E-90 |
Pvalue mlog | 89.096910013008 |
P value text | (AA) |
Or beta | 0.374 |
%95 Ci | [NR] unit decrease |
Platform | Affymetrix [~ 2500000] (imputed) |
CNV | N |
Mapped trait | arachidonic acid measurement, fatty acid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006808, http://www.ebi.ac.uk/efo/EFO_0005110 |
Study accession | GCST002712 |