Human SNP ID | rs174538 |
---|---|
Human chromosome | chr11 |
Human SNP position | 61792609 |
Pig chromosome | chr2 |
Pig SNP position | 9241225 |
PubMed ID | 21829377 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21829377 |
Study | Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. |
Disease/Trait | Phospholipid levels (plasma) |
Initial sample | 8,866 European ancestry individuals |
Replication sample | NA |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61792609 |
Reported gene | C11orf10 |
Mapped gene | TMEM258 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 746 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174538-A |
SNPs | rs174538 |
Merged | 0 |
SNP id current | 174538 |
Context | 5_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 5E-58 |
Pvalue mlog | 57.3010299956639 |
P value text | (EPA) |
Or beta | 0.08 |
%95 Ci | [NR] % decrease |
Platform | Affymetrix, Illumina [NR] |
CNV | N |
Mapped trait | phospholipid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004639 |
Study accession | GCST001178 |
PubMed ID | 24816252 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24816252 |
Study | An atlas of genetic influences on human blood metabolites. |
Disease/Trait | Blood metabolite levels |
Initial sample | 7,824 European ancestry individuals |
Replication sample | NA |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61792609 |
Reported gene | FADS1 |
Mapped gene | TMEM258 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 746 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174538-A |
SNPs | rs174538 |
Merged | 0 |
SNP id current | 174538 |
Context | 5_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.3 |
P value | 0.00000000000009 |
Pvalue mlog | 13.0457574905606 |
P value text | (docosapentaenoate (n3 DPA; 22:5n3)) |
Or beta | 0.026 |
%95 Ci | [0.018-0.034] unit decrease |
Platform | Affymetrix, Illumina [2100000] (imputed) |
CNV | N |
Mapped trait | blood metabolite measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005664 |
Study accession | GCST002443 |
PubMed ID | 25646338 |
Journal | Am J Clin Nutr |
Link | www.ncbi.nlm.nih.gov/pubmed/25646338 |
Study | Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. |
Disease/Trait | Trans fatty acid levels |
Initial sample | 8,013 European ancestry individuals |
Replication sample | 1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals |
Region | 11q12.2 |
Chromosome id | chr11 |
Chromosome position | 61792609 |
Reported gene | NR |
Mapped gene | TMEM258 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 746 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs174538-A |
SNPs | rs174538 |
Merged | 0 |
SNP id current | 174538 |
Context | 5_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.2955 |
P value | 0.000000000001 |
Pvalue mlog | 12 |
P value text | (Cis/trans-18:2, EA) |
Or beta | 0.0031 |
%95 Ci | [0.0023-0.0039] unit increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | cis/trans-18:2 fatty acid measurement, trans fatty acid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006824, http://www.ebi.ac.uk/efo/EFO_0006821 |
Study accession | GCST002721 |