SNP Detail For rs174534
1.Mapping Information
Human SNP ID rs174534
Human chromosome chr11
Human SNP position 61781986
Pig chromosome chr2
Pig SNP position 9316601
2.Annotation Information
PubMed ID26584805
JournalGenes Nutr
Linkwww.ncbi.nlm.nih.gov/pubmed/26584805
StudyA genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.
Disease/TraitPlasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)
Initial sample717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls
Replication sampleNA
Region11q12.2
Chromosome idchr11
Chromosome position61781986
Reported geneNR
Mapped geneMYRF
Upstream gene id
Downstream gene id
SNP gene ids745
Upstream gene distance
Downstream gene distance
SNP risk allelers174534-G
SNPsrs174534
Merged0
SNP id current174534
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.6663
P value1E-29
Pvalue mlog29
P value text
Or beta0.177
%95 Ci[0.15-0.21] unit decrease
PlatformIllumina [up to 1980188] (imputed)
CNVN
Mapped trait
Mapped trait URI
Study accessionGCST003237
PubMed ID25646338
JournalAm J Clin Nutr
Linkwww.ncbi.nlm.nih.gov/pubmed/25646338
StudyGenetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.
Disease/TraitTrans fatty acid levels
Initial sample8,013 European ancestry individuals
Replication sample1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals
Region11q12.2
Chromosome idchr11
Chromosome position61781986
Reported geneNR
Mapped geneMYRF
Upstream gene id
Downstream gene id
SNP gene ids745
Upstream gene distance
Downstream gene distance
SNP risk allelers174534-A
SNPsrs174534
Merged0
SNP id current174534
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.6658
P value0.00000000004
Pvalue mlog10.397940008672
P value text(Cis/trans-18:2, EA)
Or beta0.0029
%95 Ci[0.0021-0.0037] unit decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitcis/trans-18:2 fatty acid measurement, trans fatty acid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006824, http://www.ebi.ac.uk/efo/EFO_0006821
Study accessionGCST002721