SNP Detail For rs174529
1.Mapping Information
Human SNP ID rs174529
Human chromosome chr11
Human SNP position 61776489
Pig chromosome chr2
Pig SNP position 9321916
2.Annotation Information
PubMed ID25961943
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25961943
StudyThe impact of low-frequency and rare variants on lipid levels.
Disease/TraitHDL cholesterol
Initial sampleup to 62,166 European ancestry individuals
Replication sampleNA
Region11q12.2
Chromosome idchr11
Chromosome position61776489
Reported geneFADS1, FADS2, FADS3
Mapped geneMYRF
Upstream gene id
Downstream gene id
SNP gene ids745
Upstream gene distance
Downstream gene distance
SNP risk allelers174529-T
SNPsrs174529
Merged
SNP id current174529
Contextintron_variant
Intergenic0
Allele frequency0.61
P value0.00000000001
Pvalue mlog11
P value text
Or beta0.041
%95 Ci[0.029-0.053] s.d. increase
PlatformAffymetrix, Illumina, Perlegen [up to 9657952] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST002899
PubMed ID25961943
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25961943
StudyThe impact of low-frequency and rare variants on lipid levels.
Disease/TraitTriglycerides
Initial sampleup to 62,166 European ancestry individuals
Replication sampleNA
Region11q12.2
Chromosome idchr11
Chromosome position61776489
Reported geneFADS1, FADS2, FADS3
Mapped geneMYRF
Upstream gene id
Downstream gene id
SNP gene ids745
Upstream gene distance
Downstream gene distance
SNP risk allelers174529-C
SNPsrs174529
Merged
SNP id current174529
Contextintron_variant
Intergenic0
Allele frequency0.39
P value4E-20
Pvalue mlog19.397940008672
P value text
Or beta0.056
%95 Ci[0.044-0.068] s.d. increase
PlatformAffymetrix, Illumina, Perlegen [up to 9657952] (imputed)
CNVN
Mapped traittriglyceride measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004530
Study accessionGCST002897