SNP Detail For rs174528
1.Mapping Information
Human SNP ID rs174528
Human chromosome chr11
Human SNP position 61776027
Pig chromosome chr2
Pig SNP position 9322369
2.Annotation Information
PubMed ID26584805
JournalGenes Nutr
Linkwww.ncbi.nlm.nih.gov/pubmed/26584805
StudyA genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.
Disease/TraitPlasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)
Initial sample717 Singaporean Chinese ancestry myocardial infarction cases, 644 Singaporean Chinese ancestry controls
Replication sampleNA
Region11q12.2
Chromosome idchr11
Chromosome position61776027
Reported geneNR
Mapped geneMYRF
Upstream gene id
Downstream gene id
SNP gene ids745
Upstream gene distance
Downstream gene distance
SNP risk allelers174528-T
SNPsrs174528
Merged0
SNP id current174528
Contextintron_variant
Intergenic0
Allele frequency0.3337
P value2E-65
Pvalue mlog64.698970004336
P value text
Or beta0.2088
%95 Ci[0.19-0.23] unit increase
PlatformIllumina [up to 1980188] (imputed)
CNVN
Mapped traitarachidonic acid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006808
Study accessionGCST003236
PubMed ID25646338
JournalAm J Clin Nutr
Linkwww.ncbi.nlm.nih.gov/pubmed/25646338
StudyGenetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.
Disease/TraitTrans fatty acid levels
Initial sample8,013 European ancestry individuals
Replication sample1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals
Region11q12.2
Chromosome idchr11
Chromosome position61776027
Reported geneNR
Mapped geneMYRF
Upstream gene id
Downstream gene id
SNP gene ids745
Upstream gene distance
Downstream gene distance
SNP risk allelers174528-T
SNPsrs174528
Merged0
SNP id current174528
Contextintron_variant
Intergenic0
Allele frequency0.632
P value0.000000000004
Pvalue mlog11.397940008672
P value text(Cis/trans-18:2, EA)
Or beta0.003
%95 Ci[0.0022-0.0038] unit decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitcis/trans-18:2 fatty acid measurement, trans fatty acid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006824, http://www.ebi.ac.uk/efo/EFO_0006821
Study accessionGCST002721