SNP Detail For rs174468
1.Mapping Information
Human SNP ID rs174468
Human chromosome chr11
Human SNP position 61896219
Pig chromosome chr2
Pig SNP position 9185053
2.Annotation Information
PubMed ID21829377
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21829377
StudyGenetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.
Disease/TraitPhospholipid levels (plasma)
Initial sample8,866 European ancestry individuals
Replication sampleNA
Region11q12.2
Chromosome idchr11
Chromosome position61896219
Reported geneRAB3IL1
Mapped geneFADS3 - RAB3IL1
Upstream gene id3995
Downstream gene id5866
SNP gene ids
Upstream gene distance4674
Downstream gene distance1021
SNP risk allelers174468-A
SNPsrs174468
Merged0
SNP id current174468
Contextupstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.000000000001
Pvalue mlog12
P value text(ALA)
Or beta0.01
%95 Ci[NR] % decrease
PlatformAffymetrix, Illumina [NR]
CNVN
Mapped traitphospholipid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004639
Study accessionGCST001180
PubMed ID21829377
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21829377
StudyGenetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.
Disease/TraitPhospholipid levels (plasma)
Initial sample8,866 European ancestry individuals
Replication sampleNA
Region11q12.2
Chromosome idchr11
Chromosome position61896219
Reported geneRAB3IL1
Mapped geneFADS3 - RAB3IL1
Upstream gene id3995
Downstream gene id5866
SNP gene ids
Upstream gene distance4674
Downstream gene distance1021
SNP risk allelers174468-A
SNPsrs174468
Merged0
SNP id current174468
Contextupstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.00000000000000002
Pvalue mlog16.698970004336
P value text(EPA)
Or beta0.05
%95 Ci[NR] % increase
PlatformAffymetrix, Illumina [NR]
CNVN
Mapped traitphospholipid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004639
Study accessionGCST001178
PubMed ID21829377
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21829377
StudyGenetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.
Disease/TraitPhospholipid levels (plasma)
Initial sample8,866 European ancestry individuals
Replication sampleNA
Region11q12.2
Chromosome idchr11
Chromosome position61896219
Reported geneRAB3IL1
Mapped geneFADS3 - RAB3IL1
Upstream gene id3995
Downstream gene id5866
SNP gene ids
Upstream gene distance4674
Downstream gene distance1021
SNP risk allelers174468-A
SNPsrs174468
Merged0
SNP id current174468
Contextupstream_gene_variant
Intergenic1
Allele frequencyNR
P value3E-35
Pvalue mlog34.5228787452803
P value text(Docosapentaenoic acid)
Or beta0.04
%95 Ci[NR] % increase
PlatformAffymetrix, Illumina [NR]
CNVN
Mapped traitphospholipid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004639
Study accessionGCST001179