SNP Detail For rs17412740
1.Mapping Information
Human SNP ID rs17412740
Human chromosome chr8
Human SNP position 20389247
Pig chromosome chr14
Pig SNP position 4856218
2.Annotation Information
PubMed ID23551011
JournalAnn Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23551011
StudyGenome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort.
Disease/TraitPreeclampsia
Initial sample21 Afro-Caribbean cases, 1,010 Afro-Caribbean controls, 50 European ancestry cases, 1,202 European ancestry controls, 62 Hispanic cases, 658 Hispanic controls
Replication sampleNA
Region8p21.3
Chromosome idchr8
Chromosome position20389247
Reported geneLZTS1
Mapped geneLOC105379314 - LOC105379398
Upstream gene id105379314
Downstream gene id105379398
SNP gene ids
Upstream gene distance18620
Downstream gene distance16238
SNP risk allelers17412740-?
SNPsrs17412740
Merged0
SNP id current17412740
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.000002
Pvalue mlog5.69897000433601
P value text(Hispanic)
Or beta6.08
%95 Ci[2.88-12.81]
PlatformIllumina [2485249] (imputed)
CNVN
Mapped traitpreeclampsia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000668
Study accessionGCST001949