Human SNP ID | rs1738074 |
---|---|
Human chromosome | chr6 |
Human SNP position | 159044945 |
Pig chromosome | chr1 |
Pig SNP position | 10042299 |
PubMed ID | 18311140 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/18311140 |
Study | Newly identified genetic risk variants for celiac disease related to the immune response. |
Disease/Trait | Celiac disease |
Initial sample | 767 European ancestry cases, 1,422 European ancestry controls |
Replication sample | 1,643 European ancestry cases, 3,406 European ancestry controls |
Region | 6q25.3 |
Chromosome id | chr6 |
Chromosome position | 159044945 |
Reported gene | TAGAP |
Mapped gene | TAGAP, LOC105378082 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 117289, 105378082 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1738074-A |
SNPs | rs1738074 |
Merged | 0 |
SNP id current | 1738074 |
Context | 5_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.00000007 |
Pvalue mlog | 7.15490195998574 |
P value text | |
Or beta | 1.21 |
%95 Ci | [1.13-1.30] |
Platform | Illumina [310605] |
CNV | N |
Mapped trait | celiac disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001060 |
Study accession | GCST000157 |
PubMed ID | 22190364 |
Journal | Ann Neurol |
Link | www.ncbi.nlm.nih.gov/pubmed/22190364 |
Study | Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. |
Disease/Trait | Multiple sclerosis |
Initial sample | 5,545 European ancestry cases, 12,153 European ancestry controls |
Replication sample | NA |
Region | 6q25.3 |
Chromosome id | chr6 |
Chromosome position | 159044945 |
Reported gene | TAGAP |
Mapped gene | TAGAP, LOC105378082 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 117289, 105378082 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1738074-C |
SNPs | rs1738074 |
Merged | 0 |
SNP id current | 1738074 |
Context | 5_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.58 |
P value | 0.0000004 |
Pvalue mlog | 6.39794000867203 |
P value text | |
Or beta | 1.15 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [2529394] |
CNV | N |
Mapped trait | multiple sclerosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003885 |
Study accession | GCST001341 |
PubMed ID | 20190752 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20190752 |
Study | Multiple common variants for celiac disease influencing immune gene expression. |
Disease/Trait | Celiac disease |
Initial sample | 4,533 European ancestry cases, 10,750 European ancestry controls |
Replication sample | 4,918 European ancestry cases, 5,684 European ancestry controls |
Region | 6q25.3 |
Chromosome id | chr6 |
Chromosome position | 159044945 |
Reported gene | TAGAP |
Mapped gene | TAGAP, LOC105378082 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 117289, 105378082 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1738074-A |
SNPs | rs1738074 |
Merged | 0 |
SNP id current | 1738074 |
Context | 5_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.43 |
P value | 0.000000000000003 |
Pvalue mlog | 14.5228787452803 |
P value text | |
Or beta | 1.16 |
%95 Ci | [1.12-1.21] |
Platform | Illumina [292387] |
CNV | N |
Mapped trait | celiac disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001060 |
Study accession | GCST000612 |
PubMed ID | 21833088 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/21833088 |
Study | Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. |
Disease/Trait | Multiple sclerosis |
Initial sample | 9,772 European ancestry cases, 16,849 European ancestry controls |
Replication sample | 4,218 European ancestry cases, 7,296 European ancestry controls |
Region | 6q25.3 |
Chromosome id | chr6 |
Chromosome position | 159044945 |
Reported gene | TAGAP |
Mapped gene | TAGAP, LOC105378082 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 117289, 105378082 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1738074-G |
SNPs | rs1738074 |
Merged | 0 |
SNP id current | 1738074 |
Context | 5_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000000000000007 |
Pvalue mlog | 14.1549019599857 |
P value text | |
Or beta | 1.13 |
%95 Ci | [1.12-1.15] |
Platform | Illumina [465434] |
CNV | N |
Mapped trait | multiple sclerosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003885 |
Study accession | GCST001198 |