Human SNP ID | rs17356907 |
---|---|
Human chromosome | chr12 |
Human SNP position | 95633983 |
Pig chromosome | chr5 |
Pig SNP position | 92002211 |
PubMed ID | 22747683 |
---|---|
Journal | BMC Med Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22747683 |
Study | Genetic variants associated with breast size also influence breast cancer risk. |
Disease/Trait | Breast size |
Initial sample | 16,175 European ancestry female individuals |
Replication sample | NA |
Region | 12q22 |
Chromosome id | chr12 |
Chromosome position | 95633983 |
Reported gene | NEDD1, MIR135A2 |
Mapped gene | USP44 - PGAM1P5 |
Upstream gene id | 84101 |
Downstream gene id | 100132594 |
SNP gene ids | |
Upstream gene distance | 82454 |
Downstream gene distance | 15272 |
SNP risk allele | rs17356907-G |
SNPs | rs17356907 |
Merged | 0 |
SNP id current | 17356907 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.296 |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | |
Or beta | 0.081 |
%95 Ci | [0.048-0.114] cup size increase |
Platform | Illumina [7422970] (imputed) |
CNV | N |
Mapped trait | breast size, breast carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004884, http://www.ebi.ac.uk/efo/EFO_0000305 |
Study accession | GCST001585 |
PubMed ID | 23535729 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23535729 |
Study | Large-scale genotyping identifies 41 new loci associated with breast cancer risk. |
Disease/Trait | Breast cancer |
Initial sample | 10,052 European ancestry cases, 12,575 European ancestry controls |
Replication sample | 45,290 European ancestry cases, 41,880 European ancestry controls |
Region | 12q22 |
Chromosome id | chr12 |
Chromosome position | 95633983 |
Reported gene | NTN4 |
Mapped gene | USP44 - PGAM1P5 |
Upstream gene id | 84101 |
Downstream gene id | 100132594 |
SNP gene ids | |
Upstream gene distance | 82454 |
Downstream gene distance | 15272 |
SNP risk allele | rs17356907-A |
SNPs | rs17356907 |
Merged | 0 |
SNP id current | 17356907 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.7 |
P value | 2E-22 |
Pvalue mlog | 21.698970004336 |
P value text | |
Or beta | 1.1 |
%95 Ci | [1.08-1.12] |
Platform | Affymetrix, Illumina [~ 2600000] (imputed) |
CNV | N |
Mapped trait | breast carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000305 |
Study accession | GCST001937 |
PubMed ID | 23535733 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23535733 |
Study | Genome-wide association studies identify four ER negative-specific breast cancer risk loci. |
Disease/Trait | Breast cancer |
Initial sample | 4,193 European ancestry cases, 35,194 European ancestry controls |
Replication sample | 6,514 European ancestry cases, 41,455 European ancestry controls |
Region | 12q22 |
Chromosome id | chr12 |
Chromosome position | 95633983 |
Reported gene | NTN4 |
Mapped gene | USP44 - PGAM1P5 |
Upstream gene id | 84101 |
Downstream gene id | 100132594 |
SNP gene ids | |
Upstream gene distance | 82454 |
Downstream gene distance | 15272 |
SNP risk allele | rs17356907-A |
SNPs | rs17356907 |
Merged | 0 |
SNP id current | 17356907 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.702 |
P value | 0.000009 |
Pvalue mlog | 5.04575749056067 |
P value text | |
Or beta | 1.09 |
%95 Ci | [1.04-1.12] |
Platform | Illumina [NR] |
CNV | N |
Mapped trait | breast carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000305 |
Study accession | GCST001930 |