Human SNP ID | rs17319721 |
---|---|
Human chromosome | chr4 |
Human SNP position | 76447694 |
Pig chromosome | chr8 |
Pig SNP position | 76312464 |
PubMed ID | 19430482 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19430482 |
Study | Multiple loci associated with indices of renal function and chronic kidney disease. |
Disease/Trait | Renal function and chronic kidney disease |
Initial sample | 2,388 European ancestry cases, 17,489 European ancestry controls |
Replication sample | 1,932 cases, 19,534 controls |
Region | 4q21.1 |
Chromosome id | chr4 |
Chromosome position | 76447694 |
Reported gene | SHROOM3 |
Mapped gene | SHROOM3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57619 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs17319721-A |
SNPs | rs17319721 |
Merged | 0 |
SNP id current | 17319721 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.44 |
P value | 0.000000000001 |
Pvalue mlog | 12 |
P value text | (eGFRcrea) |
Or beta | 0.01 |
%95 Ci | [0.008-0.016] ml/min/1.73m2 decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | renal system measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004742 |
Study accession | GCST000397 |
PubMed ID | 20383146 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20383146 |
Study | New loci associated with kidney function and chronic kidney disease. |
Disease/Trait | Chronic kidney disease |
Initial sample | Up to 67,093 European ancestry individuals |
Replication sample | Up to 22,982 European ancestry individuals |
Region | 4q21.1 |
Chromosome id | chr4 |
Chromosome position | 76447694 |
Reported gene | CCDC158, SHROOM3 |
Mapped gene | SHROOM3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57619 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs17319721-A |
SNPs | rs17319721 |
Merged | 0 |
SNP id current | 17319721 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.43 |
P value | 1E-19 |
Pvalue mlog | 19 |
P value text | (eGFRcrea) |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | chronic kidney disease, serum creatinine measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0004518 |
Study accession | GCST000649 |