Human SNP ID | rs17277546 |
---|---|
Human chromosome | chr7 |
Human SNP position | 99891948 |
Pig chromosome | chr3 |
Pig SNP position | 7094171 |
PubMed ID | 21533175 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21533175 |
Study | Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. |
Disease/Trait | Dehydroepiandrosterone sulphate levels |
Initial sample | 14,846 European ancestry individuals |
Replication sample | NA |
Region | 7q22.1 |
Chromosome id | chr7 |
Chromosome position | 99891948 |
Reported gene | TRIM4, CYP3A43 |
Mapped gene | TRIM4 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 89122 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs17277546-A |
SNPs | rs17277546 |
Merged | 0 |
SNP id current | 17277546 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.05 |
P value | 0.00000000002 |
Pvalue mlog | 10.698970004336 |
P value text | |
Or beta | 0.11 |
%95 Ci | [0.07-0.15] umol/L decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | hormone measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004730 |
Study accession | GCST001038 |
PubMed ID | 21886157 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/21886157 |
Study | Human metabolic individuality in biomedical and pharmaceutical research. |
Disease/Trait | Metabolic traits |
Initial sample | 2,820 European ancestry individuals |
Replication sample | NA |
Region | 7q22.1 |
Chromosome id | chr7 |
Chromosome position | 99891948 |
Reported gene | CYP3A4 |
Mapped gene | TRIM4 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 89122 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs17277546-A |
SNPs | rs17277546 |
Merged | 0 |
SNP id current | 17277546 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.045 |
P value | 9E-40 |
Pvalue mlog | 39.0457574905606 |
P value text | (androsterone sulfate + 2 other traits) |
Or beta | 0.476 |
%95 Ci | [NR] unit decrease |
Platform | Affymetrix, Illumina [534665] |
CNV | N |
Mapped trait | metabolite measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004725 |
Study accession | GCST001217 |