SNP Detail For rs17178006
1.Mapping Information
Human SNP ID rs17178006
Human chromosome chr12
Human SNP position 65324519
Pig chromosome chr5
Pig SNP position 33028959
2.Annotation Information
PubMed ID22504421
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22504421
StudyCommon variants at 12q14 and 12q24 are associated with hippocampal volume.
Disease/TraitHippocampal volume
Initial sample9,232 European ancestry individuals
Replication sample2,318 European ancestry individuals
Region12q14.3
Chromosome idchr12
Chromosome position65324519
Reported geneMSRB3
Mapped geneMSRB3
Upstream gene id
Downstream gene id
SNP gene ids253827
Upstream gene distance
Downstream gene distance
SNP risk allelers17178006-G
SNPsrs17178006
Merged0
SNP id current17178006
Contextintron_variant
Intergenic0
Allele frequency0.1
P value0.00000000005
Pvalue mlog10.3010299956639
P value text
Or beta123.8
%95 Ci[86.76-160.84] mm3 decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traithippocampal volume
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005035
Study accessionGCST001485
PubMed ID25607358
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25607358
StudyCommon genetic variants influence human subcortical brain structures.
Disease/TraitSubcortical brain region volumes
Initial sampleup to 13,171 European ancestry individuals
Replication sampleup to 15,130 European ancestry individuals, 545 Japanese ancestry individuals, 736 Mexican American individuals
Region12q14.3
Chromosome idchr12
Chromosome position65324519
Reported geneMSRB3
Mapped geneMSRB3
Upstream gene id
Downstream gene id
SNP gene ids253827
Upstream gene distance
Downstream gene distance
SNP risk allelers17178006-?
SNPsrs17178006
Merged0
SNP id current17178006
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000003
Pvalue mlog6.52287874528033
P value text(Hippocampus, EA)
Or beta44.27
%95 Ci[27.43-61.11] unit increase
PlatformAffymetrix, Illumina [NR] (imputed)
CNVN
Mapped traithippocampal volume
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005035
Study accessionGCST002756