SNP Detail For rs1714746
1.Mapping Information
Human SNP ID rs1714746
Human chromosome chr8
Human SNP position 4247625
Pig chromosome chr15
Pig SNP position 40559053
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)
Initial sample261 Japanese ancestry cases, 262 Japanese ancestry controls
Replication sampleNA
Region8p23.2
Chromosome idchr8
Chromosome position4247625
Reported geneCSMD1
Mapped geneCSMD1
Upstream gene id
Downstream gene id
SNP gene ids64478
Upstream gene distance
Downstream gene distance
SNP risk allelers1714746-G
SNPsrs1714746
Merged0
SNP id current1714746
Contextintron_variant
Intergenic0
Allele frequency0.435
P value0.000007
Pvalue mlog5.15490195998574
P value text(Recessive model)
Or beta1.61
%95 Ci[1.261-2.056]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to carboplatin, response to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097328, http://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST002004