Human SNP ID | rs17118552 |
---|---|
Human chromosome | chr14 |
Human SNP position | 47405354 |
Pig chromosome | chr1 |
Pig SNP position | 197588006 |
PubMed ID | 22491018 |
---|---|
Journal | Pharmacogenomics J |
Link | www.ncbi.nlm.nih.gov/pubmed/22491018 |
Study | Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis. |
Disease/Trait | Response to tocilizumab in rheumatoid arthritis |
Initial sample | 1,157 European and other ancestry rheumatoid arthritis cases |
Replication sample | 526 European and other ancestry rheumatoid arthritis cases |
Region | 14q21.3 |
Chromosome id | chr14 |
Chromosome position | 47405354 |
Reported gene | MDGA2 |
Mapped gene | MDGA2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 161357 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs17118552-? |
SNPs | rs17118552 |
Merged | 0 |
SNP id current | 17118552 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.014 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | (CTJC , EA, RF+) |
Or beta | 17.19 |
%95 Ci | [NR] unit increase |
Platform | Illumina [534053] |
CNV | N |
Mapped trait | rheumatoid arthritis, response to drug |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685, http://purl.obolibrary.org/obo/GO_0042493 |
Study accession | GCST001476 |