SNP Detail For rs17108344
1.Mapping Information
Human SNP ID rs17108344
Human chromosome chr12
Human SNP position 70560684
Pig chromosome chr5
Pig SNP position 37275178
2.Annotation Information
PubMed ID24554482
JournalJ Neurovirol
Linkwww.ncbi.nlm.nih.gov/pubmed/24554482
StudyGenome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.
Disease/TraitResponse to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy)
Initial sample8 European ancestry cases, 12 African American cases, 3 Hispanic cases, 85 European ancestry controls, 49 African American controls, 30 Hispanic controls
Replication sampleNA
Region12q15
Chromosome idchr12
Chromosome position70560684
Reported genePTPRB
Mapped geneLOC105369828, PTPRB
Upstream gene id
Downstream gene id
SNP gene ids105369828, 5787
Upstream gene distance
Downstream gene distance
SNP risk allelers17108344-?
SNPsrs17108344
Merged0
SNP id current17108344
Contextsynonymous_variant
Intergenic0
Allele frequency
P value0.00000003
Pvalue mlog7.52287874528033
P value text(EA)
Or beta25.3
%95 Ci[NR]
PlatformIllumina [936149]
CNVN
Mapped traitresponse to reverse transcriptase inhibitor, HIV-1 infection, peripheral neuropathy
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0061479, http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0003100
Study accessionGCST002363