Human SNP ID | rs17085007 |
---|---|
Human chromosome | chr13 |
Human SNP position | 26957130 |
Pig chromosome | chr11 |
Pig SNP position | 3964307 |
PubMed ID | 21297633 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21297633 |
Study | Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. |
Disease/Trait | Ulcerative colitis |
Initial sample | 6,687 European ancestry cases, 19,718 European ancestry controls |
Replication sample | 9,628 European ancestry cases, 12,917 European ancestry controls |
Region | 13q12.13 |
Chromosome id | chr13 |
Chromosome position | 26957130 |
Reported gene | intergenic |
Mapped gene | LOC105370123 - LOC105370124 |
Upstream gene id | 105370123 |
Downstream gene id | 105370124 |
SNP gene ids | |
Upstream gene distance | 76189 |
Downstream gene distance | 89029 |
SNP risk allele | rs17085007-C |
SNPs | rs17085007 |
Merged | 0 |
SNP id current | 17085007 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.18 |
P value | 0.0000000000000001 |
Pvalue mlog | 16 |
P value text | |
Or beta | 1.16 |
%95 Ci | [1.10-1.21] |
Platform | Affymetrix, Illumina [~ 1100000] (imputed) |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST000964 |
PubMed ID | 19915573 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19915573 |
Study | A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. |
Disease/Trait | Ulcerative colitis |
Initial sample | 376 Japanese ancestry cases, 934 Japanese ancestry controls |
Replication sample | 376 Japanese ancestry cases, 1,097 Japanese ancestry controls |
Region | 13q12.13 |
Chromosome id | chr13 |
Chromosome position | 26957130 |
Reported gene | USP12 |
Mapped gene | LOC105370123 - LOC105370124 |
Upstream gene id | 105370123 |
Downstream gene id | 105370124 |
SNP gene ids | |
Upstream gene distance | 76189 |
Downstream gene distance | 89029 |
SNP risk allele | rs17085007-C |
SNPs | rs17085007 |
Merged | 0 |
SNP id current | 17085007 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.23 |
P value | 0.00000007 |
Pvalue mlog | 7.15490195998574 |
P value text | |
Or beta | 1.35 |
%95 Ci | [1.21-1.51] |
Platform | Illumina [513923] |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST000529 |
PubMed ID | 23511034 |
Journal | Inflamm Bowel Dis |
Link | www.ncbi.nlm.nih.gov/pubmed/23511034 |
Study | Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians. |
Disease/Trait | Ulcerative colitis |
Initial sample | 388 Korean ancestry cases, 739 Korean ancestry controls |
Replication sample | 810 Korean ancestry cases, 1709 Korean ancestry controls |
Region | 13q12.13 |
Chromosome id | chr13 |
Chromosome position | 26957130 |
Reported gene | intergenic |
Mapped gene | LOC105370123 - LOC105370124 |
Upstream gene id | 105370123 |
Downstream gene id | 105370124 |
SNP gene ids | |
Upstream gene distance | 76189 |
Downstream gene distance | 89029 |
SNP risk allele | rs17085007-C |
SNPs | rs17085007 |
Merged | 0 |
SNP id current | 17085007 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.17 |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | |
Or beta | 1.37 |
%95 Ci | [1.22-1.55] |
Platform | Illumina [581060] |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST001934 |
PubMed ID | 23511034 |
Journal | Inflamm Bowel Dis |
Link | www.ncbi.nlm.nih.gov/pubmed/23511034 |
Study | Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians. |
Disease/Trait | Ulcerative colitis |
Initial sample | 388 Korean ancestry cases, 739 Korean ancestry controls |
Replication sample | 417 Korean ancestry cases, 732 Korean ancestry controls |
Region | 13q12.13 |
Chromosome id | chr13 |
Chromosome position | 26957130 |
Reported gene | Intergernic |
Mapped gene | LOC105370123 - LOC105370124 |
Upstream gene id | 105370123 |
Downstream gene id | 105370124 |
SNP gene ids | |
Upstream gene distance | 76189 |
Downstream gene distance | 89029 |
SNP risk allele | rs17085007-C |
SNPs | rs17085007 |
Merged | 0 |
SNP id current | 17085007 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.18 |
P value | 0.000008 |
Pvalue mlog | 5.09691001300805 |
P value text | |
Or beta | 1.4 |
%95 Ci | [1.21-1.63] |
Platform | Illumina [581060] |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST001938 |
PubMed ID | 23128233 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/23128233 |
Study | Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. |
Disease/Trait | Inflammatory bowel disease |
Initial sample | 12,924 European ancestry cases, 21,442 European ancestry controls |
Replication sample | 25,683 European ancestry cases, 17,015 European ancestry controls |
Region | 13q12.13 |
Chromosome id | chr13 |
Chromosome position | 26957130 |
Reported gene | intergenic |
Mapped gene | LOC105370123 - LOC105370124 |
Upstream gene id | 105370123 |
Downstream gene id | 105370124 |
SNP gene ids | |
Upstream gene distance | 76189 |
Downstream gene distance | 89029 |
SNP risk allele | rs17085007-C |
SNPs | rs17085007 |
Merged | 0 |
SNP id current | 17085007 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.183 |
P value | 3E-19 |
Pvalue mlog | 18.5228787452803 |
P value text | |
Or beta | 1.106 |
%95 Ci | [1.065-1.147] |
Platform | Affymetrix, Illumina [1230000] (imputed) |
CNV | N |
Mapped trait | inflammatory bowel disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003767 |
Study accession | GCST001725 |
PubMed ID | 26192919 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26192919 |
Study | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. |
Disease/Trait | Ulcerative colitis |
Initial sample | 6,968 European ancestry cases, 20,464 European ancestry controls |
Replication sample | 10,679 European ancestry cases, 26,715 European ancestry controls, 397 Iranian ancestry cases, 342 Iranian ancestry controls, 1,239 Indian ancestry cases, 990 Indian ancestry controls, 1,134 East Asian ancestry cases, 3,719 East Asian ancestry controls |
Region | 13q12.13 |
Chromosome id | chr13 |
Chromosome position | 26957130 |
Reported gene | NR |
Mapped gene | LOC105370123 - LOC105370124 |
Upstream gene id | 105370123 |
Downstream gene id | 105370124 |
SNP gene ids | |
Upstream gene distance | 76189 |
Downstream gene distance | 89029 |
SNP risk allele | rs17085007-G |
SNPs | rs17085007 |
Merged | 0 |
SNP id current | 17085007 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.1799 |
P value | 0.0000000000000001 |
Pvalue mlog | 16 |
P value text | (EA) |
Or beta | 1.1413064 |
%95 Ci | [1.11-1.17] |
Platform | Affymetrix, Illumina [~ 9000000] (imputed) |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST003045 |