Human SNP ID | rs17032980 |
---|---|
Human chromosome | chr2 |
Human SNP position | 67075611 |
Pig chromosome | chr3 |
Pig SNP position | 78601406 |
PubMed ID | 25710658 |
---|---|
Journal | JAMA |
Link | www.ncbi.nlm.nih.gov/pubmed/25710658 |
Study | Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia. |
Disease/Trait | Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia |
Initial sample | 53 European ancestry cases with peripheral neuropathy, 156 cases without peripheral neuropathy, 10 African ancestry cases with peripheral neuropathy, 33 African ancestry cases without peripheral neuropathy, 1 Asian ancestry case with peripheral neuropathy |
Replication sample | NA |
Region | 2p14 |
Chromosome id | chr2 |
Chromosome position | 67075611 |
Reported gene | ETAA1 |
Mapped gene | LOC105374785 - LOC102800447 |
Upstream gene id | 105374785 |
Downstream gene id | 102800447 |
SNP gene ids | |
Upstream gene distance | 60507 |
Downstream gene distance | 10835 |
SNP risk allele | rs17032980-? |
SNPs | rs17032980 |
Merged | 0 |
SNP id current | 17032980 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.00000001 |
Pvalue mlog | 8 |
P value text | |
Or beta | 3.17 |
%95 Ci | [1.95-5.17] |
Platform | Affymetrix [1576016] (imputed) |
CNV | N |
Mapped trait | peripheral neuropathy, acute lymphoblastic leukemia, response to vincristine |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003100, http://www.ebi.ac.uk/efo/EFO_0000220, http://www.ebi.ac.uk/efo/EFO_0006950 |
Study accession | GCST002792 |