SNP Detail For rs17032980
1.Mapping Information
Human SNP ID rs17032980
Human chromosome chr2
Human SNP position 67075611
Pig chromosome chr3
Pig SNP position 78601406
2.Annotation Information
PubMed ID25710658
JournalJAMA
Linkwww.ncbi.nlm.nih.gov/pubmed/25710658
StudyAssociation of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia.
Disease/TraitVincristine-induced peripheral neuropathy in acute lymphoblastic leukemia
Initial sample53 European ancestry cases with peripheral neuropathy, 156 cases without peripheral neuropathy, 10 African ancestry cases with peripheral neuropathy, 33 African ancestry cases without peripheral neuropathy, 1 Asian ancestry case with peripheral neuropathy
Replication sampleNA
Region2p14
Chromosome idchr2
Chromosome position67075611
Reported geneETAA1
Mapped geneLOC105374785 - LOC102800447
Upstream gene id105374785
Downstream gene id102800447
SNP gene ids
Upstream gene distance60507
Downstream gene distance10835
SNP risk allelers17032980-?
SNPsrs17032980
Merged0
SNP id current17032980
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.00000001
Pvalue mlog8
P value text
Or beta3.17
%95 Ci[1.95-5.17]
PlatformAffymetrix [1576016] (imputed)
CNVN
Mapped traitperipheral neuropathy, acute lymphoblastic leukemia, response to vincristine
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003100, http://www.ebi.ac.uk/efo/EFO_0000220, http://www.ebi.ac.uk/efo/EFO_0006950
Study accessionGCST002792