SNP Detail For rs17019602
1.Mapping Information
Human SNP ID rs17019602
Human chromosome chr1
Human SNP position 107646236
Pig chromosome chr4
Pig SNP position 122909480
2.Annotation Information
PubMed ID25305756
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25305756
StudyDiscovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.
Disease/TraitIgA nephropathy
Initial sample1,194 Han Chinese ancestry cases, 902 Han Chinese ancestry controls, 1,553 European ancestry cases, 3,050 European ancestry controls
Replication sample2,491 East Asian ancestry cases, 1,780 East Asian ancestry controls, 2,420 European ancestry cases, 7,222 European ancestry controls
Region1p13.3
Chromosome idchr1
Chromosome position107646236
Reported geneVAV3
Mapped geneVAV3
Upstream gene id
Downstream gene id
SNP gene ids10451
Upstream gene distance
Downstream gene distance
SNP risk allelers17019602-G
SNPsrs17019602
Merged0
SNP id current17019602
Contextintron_variant
Intergenic0
Allele frequency0.19
P value0.000000007
Pvalue mlog8.15490195998574
P value text
Or beta1.17
%95 Ci[NR]
PlatformIllumina [> 1000000] (imputed)
CNVN
Mapped traitIGA glomerulonephritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004194
Study accessionGCST002655
PubMed ID25305756
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25305756
StudyDiscovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.
Disease/TraitIgA nephropathy
Initial sample1,194 Han Chinese ancestry cases, 902 Han Chinese ancestry controls, 1,553 European ancestry cases, 3,050 European ancestry controls
Replication sample2,491 East Asian ancestry cases, 1,780 East Asian ancestry controls, 2,420 European ancestry cases, 7,222 European ancestry controls
Region1p13.3
Chromosome idchr1
Chromosome position107646236
Reported geneVAV3
Mapped geneVAV3
Upstream gene id
Downstream gene id
SNP gene ids10451
Upstream gene distance
Downstream gene distance
SNP risk allelers17019602-G
SNPsrs17019602
Merged0
SNP id current17019602
Contextintron_variant
Intergenic0
Allele frequency0.19
P value0.0000008
Pvalue mlog6.09691001300805
P value text(EA)
Or beta1.19
%95 Ci[NR]
PlatformIllumina [> 1000000] (imputed)
CNVN
Mapped traitIGA glomerulonephritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004194
Study accessionGCST002655