Human SNP ID | rs16957091 |
---|---|
Human chromosome | chr15 |
Human SNP position | 42725228 |
Pig chromosome | chr1 |
Pig SNP position | 143548226 |
PubMed ID | 26183928 |
---|---|
Journal | Cancer Res |
Link | www.ncbi.nlm.nih.gov/pubmed/26183928 |
Study | Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung. |
Disease/Trait | MGMT methylation in smokers |
Initial sample | 296 European ancestry individuals with MGMT methylation, 867 European ancestry individuals without MGMT methylation |
Replication sample | 107 European and Hispanic individuals with MGMT methylation, 323 European and Hispanic individuals without MGMT methylation |
Region | 15q15.2 |
Chromosome id | chr15 |
Chromosome position | 42725228 |
Reported gene | STARD9, CDAN1, TTBK2, UBR1 |
Mapped gene | CDAN1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 146059 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs16957091-G |
SNPs | rs16957091 |
Merged | |
SNP id current | 16957091 |
Context | synonymous_variant |
Intergenic | 0 |
Allele frequency | 0.23 |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | |
Or beta | 1.7 |
%95 Ci | [1.39-2.07] |
Platform | Illumina [1599980] |
CNV | N |
Mapped trait | smoking behavior, gene methylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0006959 |
Study accession | GCST003031 |