SNP Detail For rs16957091
1.Mapping Information
Human SNP ID rs16957091
Human chromosome chr15
Human SNP position 42725228
Pig chromosome chr1
Pig SNP position 143548226
2.Annotation Information
PubMed ID26183928
JournalCancer Res
Linkwww.ncbi.nlm.nih.gov/pubmed/26183928
StudyImplication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.
Disease/TraitMGMT methylation in smokers
Initial sample296 European ancestry individuals with MGMT methylation, 867 European ancestry individuals without MGMT methylation
Replication sample107 European and Hispanic individuals with MGMT methylation, 323 European and Hispanic individuals without MGMT methylation
Region15q15.2
Chromosome idchr15
Chromosome position42725228
Reported geneSTARD9, CDAN1, TTBK2, UBR1
Mapped geneCDAN1
Upstream gene id
Downstream gene id
SNP gene ids146059
Upstream gene distance
Downstream gene distance
SNP risk allelers16957091-G
SNPsrs16957091
Merged
SNP id current16957091
Contextsynonymous_variant
Intergenic0
Allele frequency0.23
P value0.0000003
Pvalue mlog6.52287874528033
P value text
Or beta1.7
%95 Ci[1.39-2.07]
PlatformIllumina [1599980]
CNVN
Mapped traitsmoking behavior, gene methylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0006959
Study accessionGCST003031