Human SNP ID | rs16938910 |
---|---|
Human chromosome | chr8 |
Human SNP position | 74461713 |
Pig chromosome | chr4 |
Pig SNP position | 67295111 |
PubMed ID | 22491018 |
---|---|
Journal | Pharmacogenomics J |
Link | www.ncbi.nlm.nih.gov/pubmed/22491018 |
Study | Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis. |
Disease/Trait | Response to tocilizumab in rheumatoid arthritis |
Initial sample | 1,157 European and other ancestry rheumatoid arthritis cases |
Replication sample | 526 European and other ancestry rheumatoid arthritis cases |
Region | 8q21.11 |
Chromosome id | chr8 |
Chromosome position | 74461713 |
Reported gene | intergenic |
Mapped gene | GDAP1 - MIR5681A |
Upstream gene id | 54332 |
Downstream gene id | 100847058 |
SNP gene ids | |
Upstream gene distance | 94603 |
Downstream gene distance | 86830 |
SNP risk allele | rs16938910-? |
SNPs | rs16938910 |
Merged | 0 |
SNP id current | 16938910 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.011 |
P value | 0.0000004 |
Pvalue mlog | 6.39794000867203 |
P value text | (CSJC , EA, RF+) |
Or beta | 28.66 |
%95 Ci | [NR] unit increase |
Platform | Illumina [534053] |
CNV | N |
Mapped trait | rheumatoid arthritis, response to drug |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685, http://purl.obolibrary.org/obo/GO_0042493 |
Study accession | GCST001476 |