Human SNP ID | rs16914931 |
---|---|
Human chromosome | chr9 |
Human SNP position | 98330034 |
Pig chromosome | chr1 |
Pig SNP position | 268315579 |
PubMed ID | 25089948 |
---|---|
Journal | Pharmacogenet Genomics |
Link | www.ncbi.nlm.nih.gov/pubmed/25089948 |
Study | Ancestry and other genetic associations with plasma PCSK9 response to simvastatin. |
Disease/Trait | Response to simvastatin treatment (PCSK9 protein level change) |
Initial sample | 562 European ancestry individuals |
Replication sample | 287 African American individuals |
Region | 9q22.33 |
Chromosome id | chr9 |
Chromosome position | 98330034 |
Reported gene | GABBR2 |
Mapped gene | GABBR2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 9568 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs16914931-A |
SNPs | rs16914931 |
Merged | 0 |
SNP id current | 16914931 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.121 |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | (EA) |
Or beta | 0.198 |
%95 Ci | [NR] unit increase |
Platform | Illumina [570422] |
CNV | N |
Mapped trait | response to simvastatin, PCSK9 protein measurement |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_1903491, http://www.ebi.ac.uk/efo/EFO_0006899 |
Study accession | GCST002642 |