SNP Detail For rs16909898
1.Mapping Information
Human SNP ID rs16909898
Human chromosome chr9
Human SNP position 95468726
Pig chromosome chr10
Pig SNP position 30887560
2.Annotation Information
PubMed ID20010835
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/20010835
StudyMeta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.
Disease/TraitPulmonary function
Initial sample20,890 European ancestry individuals
Replication sample16,178 European ancestry individuals
Region9q22.32
Chromosome idchr9
Chromosome position95468726
Reported genePTCH1
Mapped genePTCH1, LOC100507346
Upstream gene id
Downstream gene id
SNP gene ids5727, 100507346
Upstream gene distance
Downstream gene distance
SNP risk allelers16909898-A
SNPsrs16909898
Merged0
SNP id current16909898
Contextintron_variant
Intergenic0
Allele frequency0.9
P value0.0000005
Pvalue mlog6.30102999566398
P value text(FEV1/FVC)
Or beta0.5
%95 Ci[NR] % increase
PlatformAffymetrix, Illumina [2534500] (imputed)
CNVN
Mapped traitpulmonary function measurement, FEV/FEC ratio
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST000542
PubMed ID23284291
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23284291
StudyGenome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Disease/TraitPulmonary function (interaction)
Initial sample50,047 European ancestry individuals
Replication sampleNA
Region9q22.32
Chromosome idchr9
Chromosome position95468726
Reported genePTCH1
Mapped genePTCH1, LOC100507346
Upstream gene id
Downstream gene id
SNP gene ids5727, 100507346
Upstream gene distance
Downstream gene distance
SNP risk allelers16909898-?
SNPsrs16909898
Merged0
SNP id current16909898
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000000000008
Pvalue mlog11.096910013008
P value text(FEV1/FVC, Ever-smoking)
Or beta
%95 Ci
PlatformNR [~ 2500000] (imputed)
CNVN
Mapped traitFEV/FEC ratio
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST001784