Human SNP ID | rs16892766 |
---|---|
Human chromosome | chr8 |
Human SNP position | 116618444 |
Pig chromosome | chr4 |
Pig SNP position | 23472639 |
PubMed ID | 18372905 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/18372905 |
Study | A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. |
Disease/Trait | Colorectal cancer |
Initial sample | 922 European ancestry cases, 927 European ancestry controls |
Replication sample | 17,089 European ancestry cases, 16,862 European ancestry controls, 783 cases, 664 controls |
Region | 8q23.3 |
Chromosome id | chr8 |
Chromosome position | 116618444 |
Reported gene | EIF3H |
Mapped gene | LOC105375712 - EIF3H |
Upstream gene id | 105375712 |
Downstream gene id | 8667 |
SNP gene ids | |
Upstream gene distance | 3145 |
Downstream gene distance | 26372 |
SNP risk allele | rs16892766-A |
SNPs | rs16892766 |
Merged | 0 |
SNP id current | 16892766 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.07 |
P value | 0.000000000000000003 |
Pvalue mlog | 17.5228787452803 |
P value text | |
Or beta | 1.27 |
%95 Ci | [1.20-1.34] |
Platform | Illumina [547647] |
CNV | N |
Mapped trait | colorectal cancer |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005842 |
Study accession | GCST000169 |
PubMed ID | 21761138 |
Journal | Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21761138 |
Study | Meta-analysis of new genome-wide association studies of colorectal cancer risk. |
Disease/Trait | Colorectal cancer |
Initial sample | 2,906 European ancestry cases, 3,416 European ancestry controls |
Replication sample | 8,161 European ancestry cases, 9,101 European ancestry controls |
Region | 8q23.3 |
Chromosome id | chr8 |
Chromosome position | 116618444 |
Reported gene | EIF3H |
Mapped gene | LOC105375712 - EIF3H |
Upstream gene id | 105375712 |
Downstream gene id | 8667 |
SNP gene ids | |
Upstream gene distance | 3145 |
Downstream gene distance | 26372 |
SNP risk allele | rs16892766-? |
SNPs | rs16892766 |
Merged | 0 |
SNP id current | 16892766 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.08 |
P value | 0.0000004 |
Pvalue mlog | 6.39794000867203 |
P value text | |
Or beta | 1.24 |
%95 Ci | [1.14-1.34] |
Platform | Illumina [378739] |
CNV | N |
Mapped trait | colorectal cancer |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005842 |
Study accession | GCST001161 |
PubMed ID | 26151821 |
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/26151821 |
Study | Genome-wide association study of colorectal cancer identifies six new susceptibility loci. |
Disease/Trait | Colorectal cancer |
Initial sample | 18,299 European ancestry cases, 19,656 European ancestry controls |
Replication sample | 4,725 East Asian ancestry cases, 9,969 East Asian ancestry controls |
Region | 8q23.3 |
Chromosome id | chr8 |
Chromosome position | 116618444 |
Reported gene | EIF3H |
Mapped gene | LOC105375712 - EIF3H |
Upstream gene id | 105375712 |
Downstream gene id | 8667 |
SNP gene ids | |
Upstream gene distance | 3145 |
Downstream gene distance | 26372 |
SNP risk allele | rs16892766-C |
SNPs | rs16892766 |
Merged | 0 |
SNP id current | 16892766 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.1 |
P value | 0.000000000003 |
Pvalue mlog | 11.5228787452803 |
P value text | |
Or beta | 1.2048193 |
%95 Ci | [1.15-1.26] |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | colorectal cancer |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005842 |
Study accession | GCST003017 |