SNP Detail For rs16861329
1.Mapping Information
Human SNP ID rs16861329
Human chromosome chr3
Human SNP position 186948673
Pig chromosome chr13
Pig SNP position 134123836
2.Annotation Information
PubMed ID21874001
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21874001
StudyGenome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
Disease/TraitType 2 diabetes
Initial sample5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls
Replication sample13,170 South Asian ancestry cases, 25,398 South Asian ancestry controls
Region3q27.3
Chromosome idchr3
Chromosome position186948673
Reported geneST6GAL1
Mapped geneST6GAL1
Upstream gene id
Downstream gene id
SNP gene ids6480
Upstream gene distance
Downstream gene distance
SNP risk allelers16861329-G
SNPsrs16861329
Merged0
SNP id current16861329
Contextintron_variant
Intergenic0
Allele frequency0.75
P value0.00000003
Pvalue mlog7.52287874528033
P value text
Or beta1.09
%95 Ci[1.06-1.12]
PlatformIllumina [568976]
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST001213
PubMed ID24509480
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24509480
StudyGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Disease/TraitType 2 diabetes
Initial sample12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ance
Replication sample21,491 European ancestry cases, 55,647 European ancestry controls
Region3q27.3
Chromosome idchr3
Chromosome position186948673
Reported geneST64GAL1
Mapped geneST6GAL1
Upstream gene id
Downstream gene id
SNP gene ids6480
Upstream gene distance
Downstream gene distance
SNP risk allelers16861329-C
SNPsrs16861329
Merged0
SNP id current16861329
Contextintron_variant
Intergenic0
Allele frequency0.85
P value0.000009
Pvalue mlog5.04575749056067
P value text
Or beta1.03
%95 Ci[0.96-1.10]
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST002352