Human SNP ID | rs16857031 |
---|---|
Human chromosome | chr1 |
Human SNP position | 162143120 |
Pig chromosome | chr4 |
Pig SNP position | 96285316 |
PubMed ID | 19305408 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19305408 |
Study | Common variants at ten loci influence QT interval duration in the QTGEN Study. |
Disease/Trait | QT interval |
Initial sample | 13,685 European ancestry individuals |
Replication sample | 15,854 European ancestry individuals |
Region | 1q23.3 |
Chromosome id | chr1 |
Chromosome position | 162143120 |
Reported gene | NOS1AP |
Mapped gene | NOS1AP, LOC105371475 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 9722, 105371475 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs16857031-G |
SNPs | rs16857031 |
Merged | 0 |
SNP id current | 16857031 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.14 |
P value | 1E-34 |
Pvalue mlog | 34 |
P value text | |
Or beta | 2.63 |
%95 Ci | [2.28-2.97] msec increase |
Platform | Affymetrix, Illumina [up to 2543686] (imputed) |
CNV | N |
Mapped trait | QT interval |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004682 |
Study accession | GCST000363 |
PubMed ID | 24952745 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24952745 |
Study | Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. |
Disease/Trait | QT interval |
Initial sample | Up to 70,389 European ancestry individuals, up to 672 Orcadian individuals |
Replication sample | Up to 33,316 European ancestry individuals |
Region | 1q23.3 |
Chromosome id | chr1 |
Chromosome position | 162143120 |
Reported gene | NOS1AP |
Mapped gene | NOS1AP, LOC105371475 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 9722, 105371475 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs16857031-G |
SNPs | rs16857031 |
Merged | 0 |
SNP id current | 16857031 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.132 |
P value | 7E-61 |
Pvalue mlog | 60.1549019599857 |
P value text | |
Or beta | 2.37 |
%95 Ci | [2.1-2.64] unit increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | QT interval |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004682 |
Study accession | GCST002500 |