SNP Detail For rs16856186
1.Mapping Information
Human SNP ID rs16856186
Human chromosome chr1
Human SNP position 205708998
Pig chromosome chr9
Pig SNP position 72659078
2.Annotation Information
PubMed ID22424883
JournalJ Allergy Clin Immunol
Linkwww.ncbi.nlm.nih.gov/pubmed/22424883
StudyGenome-wide association study of lung function decline in adults with and without asthma.
Disease/TraitPulmonary function decline
Initial sample1,441 European ancestry asthma cases, 2,677 European ancestry controls
Replication sample1,160 European ancestry asthma cases, 10,858 European ancestry controls
Region1q32.1
Chromosome idchr1
Chromosome position205708998
Reported geneintergenic
Mapped geneLOC105371701 - NUCKS1
Upstream gene id105371701
Downstream gene id64710
SNP gene ids
Upstream gene distance18354
Downstream gene distance3821
SNP risk allelers16856186-?
SNPsrs16856186
Merged0
SNP id current16856186
Contextdownstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.000009
Pvalue mlog5.04575749056067
P value text(FEV1 decline in asthmatics)
Or beta0.2684
%95 Ci[0.15-0.39] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitforced expiratory volume
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314
Study accessionGCST001444