SNP Detail For rs16844401
1.Mapping Information
Human SNP ID rs16844401
Human chromosome chr4
Human SNP position 3447925
Pig chromosome chr8
Pig SNP position 1759222
2.Annotation Information
PubMed ID23969696
JournalCirculation
Linkwww.ncbi.nlm.nih.gov/pubmed/23969696
StudyMultiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
Disease/TraitFibrinogen
Initial sample91,323 European ancestry individuals
Replication sample8,423 African American individuals, 1,447 Hispanic individuals
Region4p16.3
Chromosome idchr4
Chromosome position3447925
Reported geneHGFAC, LRPAP1
Mapped geneHGFAC
Upstream gene id
Downstream gene id
SNP gene ids3083
Upstream gene distance
Downstream gene distance
SNP risk allelers16844401-A
SNPsrs16844401
Merged0
SNP id current16844401
Contextmissense_variant
Intergenic0
Allele frequency0.08
P value0.00000002
Pvalue mlog7.69897000433601
P value text(EA)
Or beta0.015
%95 Ci[0.0091-0.0209] unit increase
PlatformAffymetrix, Illumina [2515567] (imputed)
CNVN
Mapped traitfibrinogen measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004623
Study accessionGCST002147