Human SNP ID | rs16844401 |
---|---|
Human chromosome | chr4 |
Human SNP position | 3447925 |
Pig chromosome | chr8 |
Pig SNP position | 1759222 |
PubMed ID | 23969696 |
---|---|
Journal | Circulation |
Link | www.ncbi.nlm.nih.gov/pubmed/23969696 |
Study | Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. |
Disease/Trait | Fibrinogen |
Initial sample | 91,323 European ancestry individuals |
Replication sample | 8,423 African American individuals, 1,447 Hispanic individuals |
Region | 4p16.3 |
Chromosome id | chr4 |
Chromosome position | 3447925 |
Reported gene | HGFAC, LRPAP1 |
Mapped gene | HGFAC |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3083 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs16844401-A |
SNPs | rs16844401 |
Merged | 0 |
SNP id current | 16844401 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.08 |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | (EA) |
Or beta | 0.015 |
%95 Ci | [0.0091-0.0209] unit increase |
Platform | Affymetrix, Illumina [2515567] (imputed) |
CNV | N |
Mapped trait | fibrinogen measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004623 |
Study accession | GCST002147 |