SNP Detail For rs16842994
1.Mapping Information
Human SNP ID rs16842994
Human chromosome chr2
Human SNP position 139869162
Pig chromosome chr15
Pig SNP position 13636032
2.Annotation Information
PubMed ID19901119
JournalJ Clin Oncol
Linkwww.ncbi.nlm.nih.gov/pubmed/19901119
StudyGermline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects.
Disease/TraitMethotrexate phramacokinetics (acute lymphoblastic leukemia)
Initial sample315 European ancestry cases, 73 African American cases, 5 Asian ancestry cases, 247 cases
Replication sampleNA
Region2q22.1
Chromosome idchr2
Chromosome position139869162
Reported geneintergenic
Mapped geneLOC105373645 - LOC105373646
Upstream gene id105373645
Downstream gene id105373646
SNP gene ids
Upstream gene distance394338
Downstream gene distance121947
SNP risk allelers16842994-C
SNPsrs16842994
Merged0
SNP id current16842994
Contextintergenic_variant
Intergenic1
Allele frequency0.02
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta
%95 Ci[NR]
PlatformAffymetrix [398699]
CNVN
Mapped traitresponse to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST000523