Human SNP ID | rs16842994 |
---|---|
Human chromosome | chr2 |
Human SNP position | 139869162 |
Pig chromosome | chr15 |
Pig SNP position | 13636032 |
PubMed ID | 19901119 |
---|---|
Journal | J Clin Oncol |
Link | www.ncbi.nlm.nih.gov/pubmed/19901119 |
Study | Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. |
Disease/Trait | Methotrexate phramacokinetics (acute lymphoblastic leukemia) |
Initial sample | 315 European ancestry cases, 73 African American cases, 5 Asian ancestry cases, 247 cases |
Replication sample | NA |
Region | 2q22.1 |
Chromosome id | chr2 |
Chromosome position | 139869162 |
Reported gene | intergenic |
Mapped gene | LOC105373645 - LOC105373646 |
Upstream gene id | 105373645 |
Downstream gene id | 105373646 |
SNP gene ids | |
Upstream gene distance | 394338 |
Downstream gene distance | 121947 |
SNP risk allele | rs16842994-C |
SNPs | rs16842994 |
Merged | 0 |
SNP id current | 16842994 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.02 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | |
Or beta | |
%95 Ci | [NR] |
Platform | Affymetrix [398699] |
CNV | N |
Mapped trait | response to antineoplastic agent |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0097327 |
Study accession | GCST000523 |