SNP Detail For rs1623879
1.Mapping Information
Human SNP ID rs1623879
Human chromosome chr3
Human SNP position 58041470
Pig chromosome chr13
Pig SNP position 43724765
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)
Initial sample261 Japanese ancestry cases, 262 Japanese ancestry controls
Replication sampleNA
Region3p14.3
Chromosome idchr3
Chromosome position58041470
Reported geneFLNB
Mapped geneFLNB
Upstream gene id
Downstream gene id
SNP gene ids2317
Upstream gene distance
Downstream gene distance
SNP risk allelers1623879-G
SNPsrs1623879
Merged0
SNP id current1623879
Contextintron_variant
Intergenic0
Allele frequency0.321
P value0.000004
Pvalue mlog5.39794000867203
P value text(Recessive model)
Or beta1.669
%95 Ci[1.297-2.148]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to carboplatin, response to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097328, http://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST002004