Human SNP ID | rs157582 |
---|---|
Human chromosome | chr19 |
Human SNP position | 44892962 |
Pig chromosome | chr6 |
Pig SNP position | 47258607 |
PubMed ID | 22399527 |
---|---|
Journal | Circ Cardiovasc Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22399527 |
Study | Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits. |
Disease/Trait | Metabolic syndrome |
Initial sample | 2,637 European ancestry cases, 7,927 European ancestry controls |
Replication sample | NA |
Region | 19q13.32 |
Chromosome id | chr19 |
Chromosome position | 44892962 |
Reported gene | APOE, TOMM40 |
Mapped gene | TOMM40 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10452 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs157582-T |
SNPs | rs157582 |
Merged | 0 |
SNP id current | 157582 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.22 |
P value | 0.00000001 |
Pvalue mlog | 8 |
P value text | (TG) |
Or beta | 0.1 |
%95 Ci | [NR] mmol/l increase |
Platform | Illumina [1257079] (imputed) |
CNV | N |
Mapped trait | metabolic syndrome |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000195 |
Study accession | GCST001436 |
PubMed ID | 22005930 |
Journal | Mol Psychiatry |
Link | www.ncbi.nlm.nih.gov/pubmed/22005930 |
Study | Genome-wide association study of Alzheimer__s disease with psychotic symptoms. |
Disease/Trait | Psychosis and Alzheimer__s disease |
Initial sample | 1,039 European ancestry cases with psychosis, 5,659 European ancestry controls, 260 European, African American and Native American ancestry cases with psychosis from 264 families |
Replication sample | NA |
Region | 19q13.32 |
Chromosome id | chr19 |
Chromosome position | 44892962 |
Reported gene | APOE |
Mapped gene | TOMM40 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10452 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs157582-? |
SNPs | rs157582 |
Merged | 0 |
SNP id current | 157582 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.26 |
P value | 9E-52 |
Pvalue mlog | 51.0457574905606 |
P value text | |
Or beta | 2.3 |
%95 Ci | [NR] |
Platform | Illumina [1847262] (imputed) |
CNV | N |
Mapped trait | Alzheimers disease, psychotic symptoms |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0005940 |
Study accession | GCST001285 |
PubMed ID | 26582766 |
Journal | Circ Cardiovasc Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26582766 |
Study | Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations. |
Disease/Trait | Triglycerides |
Initial sample | 8,344 Han Chinese ancestry individuals |
Replication sample | 14,739 Han Chinese ancestry individuals |
Region | 19q13.32 |
Chromosome id | chr19 |
Chromosome position | 44892962 |
Reported gene | APOE |
Mapped gene | TOMM40 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10452 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs157582-T |
SNPs | rs157582 |
Merged | 0 |
SNP id current | 157582 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.18 |
P value | 4E-22 |
Pvalue mlog | 21.397940008672 |
P value text | |
Or beta | 0.078 |
%95 Ci | [0.062-0.094] unit increase |
Platform | Affymetrix, Illumina [2573667] (imputed) |
CNV | N |
Mapped trait | triglyceride measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004530 |
Study accession | GCST003217 |
PubMed ID | 26421299 |
Journal | Biomed Res Int |
Link | www.ncbi.nlm.nih.gov/pubmed/26421299 |
Study | Genetic Interactions Explain Variance in Cingulate Amyloid Burden: An AV-45 PET Genome-Wide Association and Interaction Study in the ADNI Cohort. |
Disease/Trait | Cingulate cortical amyloid beta load |
Initial sample | 215 European ancestry early mild cognitive impairment cases, 152 European ancestry late mild cognitive impairment cases, 45 European ancestry Alzheimer disease cases, 190 European ancestry controls |
Replication sample | NA |
Region | 19q13.32 |
Chromosome id | chr19 |
Chromosome position | 44892962 |
Reported gene | TOMM40 |
Mapped gene | TOMM40 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10452 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs157582 -? |
SNPs | rs157582 |
Merged | 0 |
SNP id current | 157582 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.0000000000000004 |
Pvalue mlog | 15.397940008672 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Illumina [582718] |
CNV | N |
Mapped trait | amyloid-beta measurement, cingulate cortex measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005194, http://www.ebi.ac.uk/efo/EFO_0007738 |
Study accession | GCST003113 |