SNP Detail For rs1562430
1.Mapping Information
Human SNP ID rs1562430
Human chromosome chr8
Human SNP position 127375606
Pig chromosome chr4
Pig SNP position 13017779
2.Annotation Information
PubMed ID21263130
JournalJ Natl Cancer Inst
Linkwww.ncbi.nlm.nih.gov/pubmed/21263130
StudyNovel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study.
Disease/TraitBreast cancer
Initial sample2,839 European ancestry cases, 3,507 European ancestry controls
Replication sample9,041 European ancestry cases, 8,980 European ancestry controls
Region8q24.21
Chromosome idchr8
Chromosome position127375606
Reported geneintergenic
Mapped geneCASC8, CASC21
Upstream gene id
Downstream gene id
SNP gene ids727677, 103021164
Upstream gene distance
Downstream gene distance
SNP risk allelers1562430-A
SNPsrs1562430
Merged0
SNP id current1562430
Contextintron_variant
Intergenic0
Allele frequency0.6
P value0.00000000003
Pvalue mlog10.5228787452803
P value text
Or beta1.16
%95 Ci[1.11-1.22]
PlatformIllumina [~ 296114]
CNVN
Mapped traitbreast carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000305
Study accessionGCST000952
PubMed ID20453838
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/20453838
StudyGenome-wide association study identifies five new breast cancer susceptibility loci.
Disease/TraitBreast cancer
Initial sample3,659 European ancestry cases, 4,897 European ancestry controls
Replication sample12,576 European ancestry cases, 12,223 European ancestry controls
Region8q24.21
Chromosome idchr8
Chromosome position127375606
Reported geneintergenic
Mapped geneCASC8, CASC21
Upstream gene id
Downstream gene id
SNP gene ids727677, 103021164
Upstream gene distance
Downstream gene distance
SNP risk allelers1562430-T
SNPsrs1562430
Merged0
SNP id current1562430
Contextintron_variant
Intergenic0
Allele frequency0.58
P value0.0000006
Pvalue mlog6.22184874961635
P value text
Or beta1.17
%95 Ci[1.10-1.25]
PlatformIllumina [582886]
CNVN
Mapped traitbreast carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000305
Study accessionGCST000678