SNP Detail For rs1561927
1.Mapping Information
Human SNP ID rs1561927
Human chromosome chr8
Human SNP position 128555832
Pig chromosome chr4
Pig SNP position 12036347
2.Annotation Information
PubMed ID25086665
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25086665
StudyGenome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
Disease/TraitPancreatic cancer
Initial sample1,582 European ancestry cases, 5,203 European ancestry controls
Replication sample6,101 European ancestry cases, 9,194 European ancestry controls
Region8q24.21
Chromosome idchr8
Chromosome position128555832
Reported geneLINC00977, MIR1208, PVT1, MYC
Mapped geneLINC00824
Upstream gene id
Downstream gene id
SNP gene ids101927774
Upstream gene distance
Downstream gene distance
SNP risk allelers1561927-T
SNPsrs1561927
Merged0
SNP id current1561927
Contextintron_variant
Intergenic0
Allele frequency0.721
P value0.0000001
Pvalue mlog7
P value text
Or beta1.15
%95 Ci[1.09-1.2]
PlatformIllumina [608202]
CNVN
Mapped traitpancreatic carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002618
Study accessionGCST002553
PubMed ID24509480
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24509480
StudyGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Disease/TraitType 2 diabetes
Initial sample12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ance
Replication sample21,491 European ancestry cases, 55,647 European ancestry controls
Region8q24.21
Chromosome idchr8
Chromosome position128555832
Reported geneTMEM75
Mapped geneLINC00824
Upstream gene id
Downstream gene id
SNP gene ids101927774
Upstream gene distance
Downstream gene distance
SNP risk allelers1561927-C
SNPsrs1561927
Merged0
SNP id current1561927
Contextintron_variant
Intergenic0
Allele frequency
P value0.0000001
Pvalue mlog7
P value text
Or beta1.06
%95 Ci[1.04-1.09]
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST002352