SNP Detail For rs1552224
1.Mapping Information
Human SNP ID rs1552224
Human chromosome chr11
Human SNP position 72722053
Pig chromosome chr9
Pig SNP position 8033659
2.Annotation Information
PubMed ID20581827
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/20581827
StudyTwelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
Disease/TraitType 2 diabetes
Initial sample8,130 European ancestry cases, 38,987 European ancestry controls
Replication sampleUp to 34,412 European ancestry cases, 59,925 European ancestry controls
Region11q13.4
Chromosome idchr11
Chromosome position72722053
Reported geneCENTD2
Mapped geneARAP1
Upstream gene id
Downstream gene id
SNP gene ids116985
Upstream gene distance
Downstream gene distance
SNP risk allelers1552224-A
SNPsrs1552224
Merged0
SNP id current1552224
Context5_prime_UTR_variant
Intergenic0
Allele frequency
P value1E-22
Pvalue mlog22
P value text
Or beta1.14
%95 Ci[1.11-1.17]
PlatformAffymetrix, Illumina [2426886] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST000712
PubMed ID24509480
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24509480
StudyGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Disease/TraitType 2 diabetes
Initial sample12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ance
Replication sample21,491 European ancestry cases, 55,647 European ancestry controls
Region11q13.4
Chromosome idchr11
Chromosome position72722053
Reported geneCENTD2, ARAP1
Mapped geneARAP1
Upstream gene id
Downstream gene id
SNP gene ids116985
Upstream gene distance
Downstream gene distance
SNP risk allelers1552224-A
SNPsrs1552224
Merged0
SNP id current1552224
Context5_prime_UTR_variant
Intergenic0
Allele frequency0.83
P value0.0000001
Pvalue mlog7
P value text
Or beta1.13
%95 Ci[1.08-1.19]
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST002352