SNP Detail For rs1549733
1.Mapping Information
Human SNP ID rs1549733
Human chromosome chr2
Human SNP position 217607449
Pig chromosome chr15
Pig SNP position 132765966
2.Annotation Information
PubMed ID25631615
JournalGenet Epidemiol
Linkwww.ncbi.nlm.nih.gov/pubmed/25631615
StudyMeta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology.
Disease/TraitOptic disc area
Initial sample15,117 European ancestry individuals, 2,131 Erasmus Rucphen Family individuals, 2,405 Chinese ancestry individuals, 2,305 Malay ancestry individuals, 2,131 Indian ancestry individuals
Replication sampleNA
Region2q35
Chromosome idchr2
Chromosome position217607449
Reported geneDIRC3
Mapped geneDIRC3
Upstream gene id
Downstream gene id
SNP gene ids729582
Upstream gene distance
Downstream gene distance
SNP risk allelers1549733-T
SNPsrs1549733
Merged0
SNP id current1549733
Contextintron_variant
Intergenic0
Allele frequency0.21
P value0.000000004
Pvalue mlog8.39794000867203
P value text
Or beta0.031
%95 Ci[0.021-0.041] unit increase
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traitoptic disc area measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006937
Study accessionGCST002763
PubMed ID25631615
JournalGenet Epidemiol
Linkwww.ncbi.nlm.nih.gov/pubmed/25631615
StudyMeta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology.
Disease/TraitOptic disc area
Initial sample15,117 European ancestry individuals, 2,131 Erasmus Rucphen Family individuals, 2,405 Chinese ancestry individuals, 2,305 Malay ancestry individuals, 2,131 Indian ancestry individuals
Replication sampleNA
Region2q35
Chromosome idchr2
Chromosome position217607449
Reported geneDIRC3
Mapped geneDIRC3
Upstream gene id
Downstream gene id
SNP gene ids729582
Upstream gene distance
Downstream gene distance
SNP risk allelers1549733-T
SNPsrs1549733
Merged0
SNP id current1549733
Contextintron_variant
Intergenic0
Allele frequency0.21
P value0.00000008
Pvalue mlog7.09691001300805
P value text(EA)
Or beta0.033
%95 Ci[0.021-0.045] unit increase
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traitoptic disc area measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006937
Study accessionGCST002763