SNP Detail For rs1541374
1.Mapping Information
Human SNP ID rs1541374
Human chromosome chr4
Human SNP position 105127203
Pig chromosome chr8
Pig SNP position 125154353
2.Annotation Information
PubMed ID21946350
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21946350
StudyGenome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
Disease/TraitPulmonary function
Initial sample48,201 European ancestry individuals
Replication sample46,411 European ancestry individuals
Region4q24
Chromosome idchr4
Chromosome position105127203
Reported geneTET2
Mapped geneLOC643675 - TET2
Upstream gene id643675
Downstream gene id54790
SNP gene ids
Upstream gene distance140502
Downstream gene distance18672
SNP risk allelers1541374-T
SNPsrs1541374
Merged0
SNP id current1541374
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.0000006
Pvalue mlog6.22184874961635
P value text(FEV1)
Or beta0.026
%95 Ci[0.016-0.036] unit decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitpulmonary function measurement, forced expiratory volume
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0004314
Study accessionGCST001251