Human SNP ID | rs1539909 |
---|---|
Human chromosome | chr18 |
Human SNP position | 71581359 |
Pig chromosome | chr1 |
Pig SNP position | 167928856 |
PubMed ID | 22569225 |
---|---|
Journal | Pharmacogenet Genomics |
Link | www.ncbi.nlm.nih.gov/pubmed/22569225 |
Study | Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis. |
Disease/Trait | Response to TNF-alpha inhibitors in rheumatoid arthritis |
Initial sample | 196 European ancestry cases |
Replication sample | NA |
Region | 18q22.3 |
Chromosome id | chr18 |
Chromosome position | 71581359 |
Reported gene | CBLN2 |
Mapped gene | LINC01541 - LOC105372186 |
Upstream gene id | 100505776 |
Downstream gene id | 105372186 |
SNP gene ids | |
Upstream gene distance | 2403 |
Downstream gene distance | 61332 |
SNP risk allele | rs1539909-? |
SNPs | rs1539909 |
Merged | 0 |
SNP id current | 1539909 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | (Relative change in DAS28) |
Or beta | |
%95 Ci | |
Platform | Illumina [486450] |
CNV | N |
Mapped trait | rheumatoid arthritis, response to TNF antagonist |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0004653 |
Study accession | GCST001510 |