SNP Detail For rs1539909
1.Mapping Information
Human SNP ID rs1539909
Human chromosome chr18
Human SNP position 71581359
Pig chromosome chr1
Pig SNP position 167928856
2.Annotation Information
PubMed ID22569225
JournalPharmacogenet Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/22569225
StudyInvestigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis.
Disease/TraitResponse to TNF-alpha inhibitors in rheumatoid arthritis
Initial sample196 European ancestry cases
Replication sampleNA
Region18q22.3
Chromosome idchr18
Chromosome position71581359
Reported geneCBLN2
Mapped geneLINC01541 - LOC105372186
Upstream gene id100505776
Downstream gene id105372186
SNP gene ids
Upstream gene distance2403
Downstream gene distance61332
SNP risk allelers1539909-?
SNPsrs1539909
Merged0
SNP id current1539909
Contextupstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.000004
Pvalue mlog5.39794000867203
P value text(Relative change in DAS28)
Or beta
%95 Ci
PlatformIllumina [486450]
CNVN
Mapped traitrheumatoid arthritis, response to TNF antagonist
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0004653
Study accessionGCST001510